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Overview
In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Over 80 authors from around the globe contribute to the two volumes, including many leading experts in their respective subjects. They encompass topics from across the diverse field of bioinformatics through its broad scope, combining to provide an inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists.
Synopsis
Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume I: Data, Sequence Analysis and Evolution examines a selection of methods involving the generation and organization of data, including sequence data, RNA and protein structures, microarray expression data and functional annotations, methods for discovering the functional components of genomes, whether they be genes, alternative splice sites, non-coding RNAs or regulatory motifs, and several of the most interesting methods in phylogenetics and evolution. As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.
Comprehensive and cutting-edge, Bioinformatics: Volume I: Data, Sequence Analysis and Evolution is an ideal reference for all scientists involved with the ever-growing array of data in the expanding field of life science.
Doody Review Services
Reviewer:Basabi Rana, Ph.D.(Loyola University Stritch School of Medicine)
Description:This precise description of all current molecular biology techniques is an important addition to the field of bioinformatics.
Purpose:The purpose is to provide a "detailed description and implantation advice" about current molecular biology techniques.
Audience:According to the author, the book is written primarily for students and beginning bioinformatics researchers. The authors have fulfilled their objective. There are quite a few contributing authors, who are authorities in the field of molecular biology and bioinformatics.
Features:A wide variety of topics involving molecular biology techniques relevant for bioinformatics researchers are covered. This volume contains three sections composed of 24 chapters and an index and evolution index. Section I deals with data and databases with six chapters on data management, RNA and protein structure determination, microarray analysis, and functional annotations. Section II on sequence analysis describes sequence alignment and the methods used for discovering functional components of genomes including genes, alternative splice sites, noncoding RNAs and regulatory motifs. Section III, the largest section with 12 chapters, covers the methods of phylogenetics and evolution, describing both basic aspects of modeling of evolution and inferring trees as well as more complex issues such as drawing inferences on ancestral gene order, genome rearrangements, and ancestral interaction networks. This section ends with a chapter that describes the achievements and challenges of algorithm in phylogenetics. The authors have included both an index and an evolution index at the end, which will be very helpful to readers.
Assessment:This is a very good reference for students who are beginning level bioinformatics researchers.
Editorials
Reviewer: Basabi Rana, Ph.D.(Loyola University Stritch School of Medicine)
Description: This precise description of all current molecular biology techniques is an important addition to the field of bioinformatics.
Purpose: The purpose is to provide a "detailed description and implantation advice" about current molecular biology techniques.
Audience: According to the author, the book is written primarily for students and beginning bioinformatics researchers. The authors have fulfilled their objective. There are quite a few contributing authors, who are authorities in the field of molecular biology and bioinformatics.
Features: A wide variety of topics involving molecular biology techniques relevant for bioinformatics researchers are covered. This volume contains three sections composed of 24 chapters and an index and evolution index. Section I deals with data and databases with six chapters on data management, RNA and protein structure determination, microarray analysis, and functional annotations. Section II on sequence analysis describes sequence alignment and the methods used for discovering functional components of genomes including genes, alternative splice sites, noncoding RNAs and regulatory motifs. Section III, the largest section with 12 chapters, covers the methods of phylogenetics and evolution, describing both basic aspects of modeling of evolution and inferring trees as well as more complex issues such as drawing inferences on ancestral gene order, genome rearrangements, and ancestral interaction networks. This section ends with a chapter that describes the achievements and challenges of algorithm in phylogenetics. The authors have included both an index and an evolution index at the end, which will be very helpful to readers.
Assessment: This is a very good reference for students who are beginning level bioinformatics researchers.