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Overview
The ability to successfully clone genes underlies the majority of our knowledge in molecular and cellular biology. Gene Cloning introduces the diverse array of techniques available to clone genes and how they can be used effectively both in the research laboratory, to gain knowledge about the gene, and for use in biotechnology, medicine, the pharmaceutical industry, and agriculture. It shows how cloning genes is an integral part of genomics and underlines its relevance in the post-genomic age, as a tool required to test predictions of gene regulation and function made through bioinformatics. Applications of gene cloning in medicine, both for diagnosis and treatment, and in the pharmaceutical industry and agriculture, are also covered in the book.
Gene Cloning takes a fresh approach to teaching molecular and cellular biology and will be a valuable resource to both undergraduates and lecturers of biological and biomedical science courses.
Synopsis
The ability to successfully clone genes underlies the majority of our knowledge in molecular and cellular biology. Gene Cloning introduces the diverse array of techniques available to clone genes and how they can be used effectively both in the research laboratory, to gain knowledge about the gene, and for use in biotechnology, medicine, the pharmaceutical industry, and agriculture. It shows how cloning genes is an integral part of genomics and underlines its relevance in the post-genomic age, as a tool required to test predictions of gene regulation and function made through bioinformatics. Applications of gene cloning in medicine, both for diagnosis and treatment, and in the pharmaceutical industry and agriculture, are also covered in the book.
Gene Cloning takes a fresh approach to teaching molecular and cellular biology and will be a valuable resource to both undergraduates and lecturers of biological and biomedical science courses.
Doody Review Services
Reviewer:Eugene A Davidson, PhD(Georgetown University School of Medicine)
Description:This book, for a course in molecular biology, assumes that the student will have been introduced to basic biochemistry, including aspects of information flow, DNA structure, etc.
Purpose:The goal is to provide a text for a senior level course in gene cloning/molecular biology. This worthwhile objective is well achieved.
Audience:The target audience is really the instructor of the course where the material is taught. Students taking the course are the secondary audience. Either way, the authors have chosen well. Although not household names in the scientific arena, the authors clearly have taught this material and know how it should be done.
Features:An initial chapter on the organization of genomes is followed by material on gene cloning, use of DNA libraries, sequencing, bioinformatics, protein expression, and the utilization of transgenic organisms. Each of the 12 main chapters has illustrative examples and sample problems as well as a short supplemental reading list that highlights key contributions from the primary literature. The flow of material is logical and the presentation clear. In addition, the information is current and largely, if not completely, error free. Instructors seeking a text for a course in molecular biology would be wise to consider this one. The authors are to be commended for a readable and well organized presentation.
Assessment:This is a strong effort. The presentation is logical, the level correct. Were I to teach a course in this area, this book would be high on my list.
Editorials
From the Publisher
'Had I ever been a practical molecular biologist, this is the book that would reassure me of the principles behind my experiments. Furthermore, if, for example, I wanted to find the transcription starting point of a gene, this would tell me the theory behind how to do it. Thus it is not a lab cookbook or manual, but a very user-friendly and helpful adviser. I was rather impressed with this book and will suggest it as a text, not only for my second and third year students but also for our MSc molecular genetics course.' - The Times Higher Education Supplement, February 23rd 2007'Instructors seeking a text for a course in molecular biology would be wise to consider this one. The authors are to be commended for a readable and well organized presentation.
This is a strong effort. The presentation is logical, the level correct. Were I to teach a course in this area, this book would be high on my list.' - Eugene A Davidson, PhD, Georgetown University School of Medicine, Doody's Reviews, April 2007
'The writing is clear and concise and, importantly for beginners, the essential information is not lost amongst a myriad of details. The instructor will find an excellent combination of traditional and up-to-date topics treated and will be able to easily complement this with information from the literature or laboratory.' - BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, Vol. 36, 2008
From The Critics
Reviewer: Eugene A Davidson, PhD(Georgetown University School of Medicine)Description: This book, for a course in molecular biology, assumes that the student will have been introduced to basic biochemistry, including aspects of information flow, DNA structure, etc.
Purpose: The goal is to provide a text for a senior level course in gene cloning/molecular biology. This worthwhile objective is well achieved.
Audience: The target audience is really the instructor of the course where the material is taught. Students taking the course are the secondary audience. Either way, the authors have chosen well. Although not household names in the scientific arena, the authors clearly have taught this material and know how it should be done.
Features: An initial chapter on the organization of genomes is followed by material on gene cloning, use of DNA libraries, sequencing, bioinformatics, protein expression, and the utilization of transgenic organisms. Each of the 12 main chapters has illustrative examples and sample problems as well as a short supplemental reading list that highlights key contributions from the primary literature. The flow of material is logical and the presentation clear. In addition, the information is current and largely, if not completely, error free. Instructors seeking a text for a course in molecular biology would be wise to consider this one. The authors are to be commended for a readable and well organized presentation.
Assessment: This is a strong effort. The presentation is logical, the level correct. Were I to teach a course in this area, this book would be high on my list.