The Human Brain Circulation

The Human Brain Circulation offers an original, up-to-date synthesis and summary of our current knowledge of the cerebrovascular circulatory system, with special emphasis on the study of isolated vessels. The contributors describe the normal vasculature and the many complex changes that occur with age and disease. Fetal and newborn circulation is also addressed. In areas where knowledge of human vessels is deficient, research on animal tissues is included.

The book is significant because it challenges some of the traditional assumptions based on animal studies of the mechanisms that control human brain vasculature and presents a contemporary view that includes the role of shear stress and intravascular pressure on the arterial circulation.

Among the topics discussed are the receptors for vasoactive substances; the molecular aspects of endothelial function in hemostasis; inflammation and thrombosis; the effect of hypertension; the pathophysiology of vasospasm, ischemia, and reperfusion; and the actions of free radicals. Techniques for the in vivo study of cerebrovascular dysfunction are also described.

The Human Brain Circulation presents a definitive understanding of this centrally important vascular bed and clearly defines the future direction for research into human cerebrovascular disease and its treatment.

The book contains black-and-white illustrations.

The Human Brain Circulation offers an original, up-to-date synthesis and summary of our current knowledge of the cerebrovascular circulatory system, with special emphasis on the study of isolated vessels. The contributors describe the normal vasculature and the many complex changes that occur with age and disease. Fetal and newborn circulation is also addressed. In areas where knowledge of human vessels is deficient, research on animal tissues is included.

The book is significant because it challenges some of the traditional assumptions based on animal studies of the mechanisms that control human brain vasculature and presents a contemporary view that includes the role of shear stress and intravascular pressure on the arterial circulation.

Among the topics discussed are the receptors for vasoactive substances; the molecular aspects of endothelial function in hemostasis; inflammation and thrombosis; the effect of hypertension; the pathophysiology of vasospasm, ischemia, and reperfusion; and the actions of free radicals. Techniques for the in vivo study of cerebrovascular dysfunction are also described.

The Human Brain Circulation presents a definitive understanding of this centrally important vascular bed and clearly defines the future direction for research into human cerebrovascular disease and its treatment.

Mukesh Misra

This is an excellent collection of work compiled by various distinguished authors presented in a conference of the same title. The purpose is to analyze the current research work done in human brain circulation. It also focuses on the future direction for research in the nature of human cerebrovascular disease. The book is meant to be for residents and medical practitioners in various disciplines, primarily pharmacology, physiology, neurology, anesthesia, etc. The research work mainly of normal vascularization and their changes with emphasis on isolated vessels is outstanding. The book defines future directions for research in human cerebrovascular diseases and its treatment. It includes a synposis and the potentialities of newer imaging techniques. This is a very readable book for residents and practitioners in various fields in regard to human brain circulation. This book will definitely be a good guide for the other researchers working in the field. It is recommended for the library and for individuals working in the area of brain circulation.

Bevan, Rosemary D. (Univ of Vermont); Bevan, John A. (Univ of Vermont)

The contributors represent the specialties of pharmacology, physiology, pathology, pharmacology, anatomy, internal medicine, histology, neurology, and surgery. Most come from the U.S., Sweden, Canada, France, Japan, Ireland, and Germany. Institutions prominently represented include Univ Hospital Lund-Sweden, Harvard Medical School, and Loma Linda Univ of Medicine.