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Overview
This two-volume set investigates the interaction of organic compounds with various forms of life, including macromolecules, enzymes, and organelles. It provides an introduction to the Hammett equation and its applications, as well as a discussion of the design of bioactive compounds. Volume 2 includes extensive tables of approximately 17,000 partition coefficients from octanol-water and a comprehensive listing of electronic and steric parameters in the design and study of bioactive organic compounds.
Editorials
Booknews
A two-volume set on quantitative structure-activity relationships (QSAR), a field that has had a significant impact on a number of areas of chemistry and biology. Volume 1, Fundamentals and Applications in Chemistry and Biology (2987-2), is a textbook that presents an introduction to QSAR and provides substituent constants for their construction. Throughout the text, QSAR in biological processes are related to those in physical organic chemistry. Because a crucial factor in advancing QSAR is the best possible database of parameters, Volume 2, Hydrophobic, Electronic, and Steric Constants (2991-0) contains comprehensive tables of physicochemical parameters. Data in these tables, which the authors have collected over 25 years, is necessary for QSAR and qualitative SAR. Annotation c. Book News, Inc., Portland, OR (booknews.com)Book Details
Published
December 1, 1994
Publisher
Washington, DC : American Chemical Society, 1995.
Pages
584
Format
Paperback
ISBN
9780841229884