Overview
Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.
The book contains both black-and-white and color illustrations.
This book gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in color to illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide range of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.
Editorials
Candace J. Krepel
This text provides an excellent overview of protein structure and how structure and function interrelate. The previous edition was published in 1991. The purpose is to convey an understanding of protein structure as a basis for the understanding of biological reactions. The text is written at a content level consistent with advanced undergraduates or above. A basic knowledge of proteins and their biological function is assumed. Basic protein structure (primary, secondary, etc.) is reviewed, followed by elucidation of the structures of examples from various protein families (that is, proteins with common functions), and to demonstrate how function follows form. The editors use excellent interrelated illustrations that allow the reader to understand the three-dimensional aspects of the structures. Amino acid sequence is listed, secondary structure of alpha helixes and beta sheets are shown, then three-dimensional models and drawings demonstrate the tertiary structure. The editors use these to show how the proteins intersect and interact with the biological environment. They do an excellent job of showing proteins as being an important part of the living organism. The text offers an up-to-date look at what is known about protein structure and the methodologies for determining structure. The editors use well-chosen paradigms as examples. In this rapidly growing field, this new edition is welcome.From The Critics
Reviewer: Candace J. Krepel, MS (Medical College of Wisconsin)Description: This text provides an excellent overview of protein structure and how structure and function interrelate. The previous edition was published in 1991.
Purpose: The purpose is to convey an understanding of protein structure as a basis for the understanding of biological reactions.
Audience: The text is written at a content level consistent with advanced undergraduates or above. A basic knowledge of proteins and their biological function is assumed.
Features: Basic protein structure (primary, secondary, etc.) is reviewed, followed by elucidation of the structures of examples from various protein families (that is, proteins with common functions), and to demonstrate how function follows form. The editors use excellent interrelated illustrations that allow the reader to understand the three-dimensional aspects of the structures. Amino acid sequence is listed, secondary structure of alpha helixes and beta sheets are shown, then three-dimensional models and drawings demonstrate the tertiary structure. The editors use these to show how the proteins intersect and interact with the biological environment. They do an excellent job of showing proteins as being an important part of the living organism.
Assessment: The text offers an up-to-date look at what is known about protein structure and the methodologies for determining structure. The editors use well-chosen paradigms as examples. In this rapidly growing field, this new edition is welcome.
Booknews
Illustrates (in clear color diagrams) and explains for both biologists and chemists the structural and functional logic that has emerged from the latest accumulated data on protein structures. Annotation c. Book News, Inc., Portland, OR (booknews.com)5 Stars! from Doody