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Oncology, Radiology & Diagnostic Imaging, Biology - General & Miscellaneous, Cytology - General & Miscellaneous, Biology - Radiobiology
Basic Clinical Radiobiology by G. Gordon Steel β€” book cover

Basic Clinical Radiobiology

by G. Gordon Steel
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Overview

This concise, but comprehensive textbook sets out all the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology. The fully updated 3rd edition continues to discuss the basis of radiation therapy and presents the principles and significant scientific developments that underlie current attempts to improve the radiotherapeutic managemnet of all cancers.

New topics in the 3rd edition include chapters on volume effects in normal tissues and the L-Q approach in clinical practice, with major revisions to sections on cell proliferation, radiation cytogenetics, radiotherapy-related morbidity, hyperfractionation and individualisation of radiotherapy. The book continues to provide invaluable advice for trainee and practising radiation oncologists from a team of internationally respected contributors and draws on the considerable experience of the Editor, gained during his time as Course Director of the annual ESTRO course in Basic Clinical Radiobiology.

About the Author, G. Gordon Steel

The Institute of Cancer Research, Sutton (Emeritus)

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Editorials

From The Critics

Reviewer: James G Douglas, MD, MS(Indiana University School of Medicine)
Description: As its title implies, this book is an update on the basics of clinical radiobiology, a field continues to rapidly change. The previous editions were published in 1993 and in 1998.
Purpose: The purpose is to outline radiobiological principles for radiation therapists, radiation physicists, and radiobiologists who act as support personnel on the radiotherapy team. The book originated from educational courses given over the years at the annual ESTRO meetings (European Society of Therapeutic Radiation Oncologists) and is directed at an international audience. It is designed to examine the basic tenets of radiobiology as they apply clinically to the practice of radiotherapy for support personnel and clearly meets these objectives.
Audience: This book is directed primarily at support persons including radiation therapists, clinical physicists, and radiobiologists. It is appropriate for this group, but it also is a good introduction to radiobiology for medical students and residents in radiation oncology and would be useful as a reference for medical oncologists.
Features: As cited in the introduction of the book "Radiotherapy is one of the two most effective treatments for cancer." It is imperative for those treating patients with this modality to understand the basics of radiobiology. These basic principles are covered well in a logical fashion including the kinetics of cell division and organization of normal tissues, the response of normal as well as tumor tissues to irradiation, the mechanism of cell kill induced by radiation, and the clinically relevant associations of volume treated, time-dose relationships, fractionation effect, and role of oxygenation in radiotherapy. Descriptions of the radiobiology of brachytherapy and particle beam irradiation are also discussed in detail. The figures are well organized and easy to read. The references are relevant and up to date. The only shortcoming is the lack of a description of molecular biologic modifications related to the effects of radiotherapy, but given the audience for which this work is intended, this is probably beyond the scope of this book's.
Assessment: This is a concise, well organized, easy to read explanation of basic radiobiological tenets which are essential to know for those in the radiotherapy community. It is shorter and less in depth than Hall's Radiobiology for the Radiologist, 5th edition (Lippincott Williams & Wilkins, 2000), particularly in the area of molecular biologic and cell cycle interactions, but this work is intended for a different audience than Hall's book. This is a welcome update.

3 Stars from Doody

Book Details

Published
July 31, 2002
Publisher
Hodder Arnold
Pages
280
Format
Hardcover
ISBN
9780340807835

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