Overview
Metal and metalloid-containing compounds exhibit a wide range of biological and biocidal activities, some of which have been employed in medicines and drugs. Polymers containing metal or metalloid functions become a natural extension of this effort; just as organic compound drugs have been chemically bound to polymers or physically imbibed into polymer matrices in order to provide a variety of useful advantages, the same opportunities exist for using metal and metalloid species. This volume will cover important biomedical applications of organometallic compounds, including metal-labeled DNA on surfaces, artificial metallo-DNA, organotin molecules as anti-cancer drugs, and much more.* Provides useful descriptions of biomedical applications for the reader to apply in his/her research into materials, polymers, and medicine/drug development.
* Edited by high-quality team of macromolecular experts from around the world
Synopsis
Edited by a five-person team of North American academic chemists, this is the third volume of a new series dedicated to the chemistry of large structures where the metal and metalloid atoms are (largely) covalently bonded into the macromolecular network within or pendant to the polymer backbone. This volume focuses on biomedical applications, with eight papers examining such topics as metal- labeled DNA on surfaces, organotin macromolecules as anticancer drugs, polymeric ferrocene conjugates as antiproliferative agents, polymeric platinum-containing drugs in the treatment of cancer, and new organic polyacid-inorganic compounds for improved dental materials. Annotation © 2004 Book News, Inc., Portland, OR
Editorials
From the Publisher
"This volume will make its creators fell well-deserved pride." (Journal of Metals Online, July 21, 2005)"β¦provides a nice overview of the fieldβ¦" (Polymer News, June 2005)
"β¦a good representative treatment of current biological and medicinal applications of organometallic polymers." (Journal of the American Chemical Society, March 31, 2005)