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Book cover of Causes and Control of Colorectal Cancer: A Model for Cancer Prevention
Oncology, Internal Medicine, Oncology - Basic Science

Causes and Control of Colorectal Cancer: A Model for Cancer Prevention

by Gabriel A. Kune (Editor)
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Overview

Causes and Control of Colorectal Cancer: A Model for Cancer Prevention is a ground- breaking monograph which takes a global, multidisciplinary approach to the causes, carcinogenesis and control of colorectal cancer. Over 1000 key studies were analyzed on colorectal cancer cause, carcinogenesis, primary prevention, early detection using modern screening techniques, and surveillance after tumor excision. All major research results are included up to the date of publication.
The key chapters include those on morphology, molecular biology and evolution of tumors, etiology chapters on heredity, diet, alcohol, smoking, physical activity, life stress and others, while major chapters in the area of colorectal cancer control are on primary prevention, early detection by screening and surveillance, and post-tumor excision surveillance. Important recommendations on primary prevention, screening and surveillance of colorectal tumors are made in keeping with the most current research data.
Causes and Control of Colorectal Cancer: A Model for Cancer Prevention takes colorectal cancer control into the 21st century, and suggests this to be the first cancer in which control will be largely achieved within the next generation, as a result of the unprecedented multidisciplinary research into causation, primary prevention, screening and surveillance over the past 30 years. The book also serves as a model for the control of other common malignancies, particularly cancers of the breast and prostate, the causes and prevention of which are less well understood.

The book contains black-and-white illustrations.

Synopsis

Causes and Control of Colorectal Cancer: A Model for Cancer Prevention is a ground- breaking monograph which takes a global, multidisciplinary approach to the causes, carcinogenesis and control of colorectal cancer. Over 1000 key studies were analyzed on colorectal cancer cause, carcinogenesis, primary prevention, early detection using modern screening techniques, and surveillance after tumor excision. All major research results are included up to the date of publication.
The key chapters include those on morphology, molecular biology and evolution of tumors, etiology chapters on heredity, diet, alcohol, smoking, physical activity, life stress and others, while major chapters in the area of colorectal cancer control are on primary prevention, early detection by screening and surveillance, and post-tumor excision surveillance. Important recommendations on primary prevention, screening and surveillance of colorectal tumors are made in keeping with the most current research data.
Causes and Control of Colorectal Cancer: A Model for Cancer Prevention takes colorectal cancer control into the 21st century, and suggests this to be the first cancer in which control will be largely achieved within the next generation, as a result of the unprecedented multidisciplinary research into causation, primary prevention, screening and surveillance over the past 30 years. The book also serves as a model for the control of other common malignancies, particularly cancers of the breast and prostate, the causes and prevention of which are less well understood.

About the Author, Gabriel A. Kune

Professor Gabriel A. Kune, MD, FRACS, FRCS(England), FACS, is a Gastrointestinal Surgeon, Professor of Surgery, University of Melbourne, Australia, and Consultant Surgeon, The Royal Melbourne Hospital. He is a past Hunterian Professor of the Royal College of Surgeons of England and has lectured extensively in the U.S.A., Europe, Australasia, Japan and South America.
In 1978 he established the large population-based Melbourne Colorectal Cancer Study, which examined all aspects of colorectal cancer incident, cause, prevention and survival, and is one of the most referenced studies in this field, the results of which have been widely published. Professor Kune is committed to the future successful control of colorectal cancer, and of the other common cancers also.

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Editorials

David L. Nahrwold

This is a highly organized compendium of the known and suspected causes of colorectal cancer and current knowledge about its prevention and control. Introductory chapters describe the molecular evolution of colorectal cancer and the relationships between adenomas and cancer. The effects of heredity, demographics, and lifestyle factors, such as alcohol consumption, diet, smoking, physical activity, radiation, personality, and even religiosity, are detailed individually in 12 chapters. Chapters on prevention and control, including screening and postsurgical surveillance, round out the book. The purpose was to ""assemble the current knowledge about colorectal tumor cause and control"" from all disciplines. He hopes that this approach will lead to the prevention and control of colorectal cancer and will be used for the study of other cancers. This effort is worthwhile. The book is valuable to researchers in the fields of medicine, epidemiology, molecular biology, anthropology, public health, biostatistics, and other life sciences. The author, Professor of Surgery Emeritus at the University of Melbourne, is an authority on the subject and wrote all but one chapter, using data compiled by his associates from the Melbourne Colorectal Cancer Study. The author does not make carefully constructed judgments about the value of most information presented, but he makes many speculations. The reader often needs additional information; fortunately, the text is extensively referenced and the index is very detailed. Helpful tables organize complex data into manageable sets. The work is valuable because the information from many disciplines is brought into a single volume. Researchers interestedin colorectal cancer should purchase it. Libraries should have it. The surgeon or gastroenterologist may find the data interesting, but the recommendations for surveillance after polypectomy and cancer surgery need more justification than is provided.

From The Critics

Reviewer: David L. Nahrwold, MD(Northwestern University Feinberg School of Medicine)
Description: This is a highly organized compendium of the known and suspected causes of colorectal cancer and current knowledge about its prevention and control. Introductory chapters describe the molecular evolution of colorectal cancer and the relationships between adenomas and cancer. The effects of heredity, demographics, and lifestyle factors, such as alcohol consumption, diet, smoking, physical activity, radiation, personality, and even religiosity, are detailed individually in 12 chapters. Chapters on prevention and control, including screening and postsurgical surveillance, round out the book.
Purpose: The purpose was to "assemble the current knowledge about colorectal tumor cause and control" from all disciplines. He hopes that this approach will lead to the prevention and control of colorectal cancer and will be used for the study of other cancers. This effort is worthwhile.
Audience: The book is valuable to researchers in the fields of medicine, epidemiology, molecular biology, anthropology, public health, biostatistics, and other life sciences. The author, Professor of Surgery Emeritus at the University of Melbourne, is an authority on the subject and wrote all but one chapter, using data compiled by his associates from the Melbourne Colorectal Cancer Study.
Features: The author does not make carefully constructed judgments about the value of most information presented, but he makes many speculations. The reader often needs additional information; fortunately, the text is extensively referenced and the index is very detailed. Helpful tables organize complex data into manageable sets.
Assessment: The work is valuable because the information from many disciplines is brought into a single volume. Researchers interested in colorectal cancer should purchase it. Libraries should have it. The surgeon or gastroenterologist may find the data interesting, but the recommendations for surveillance after polypectomy and cancer surgery need more justification than is provided.

3 Stars from Doody

Book Details

Published
July 31, 2012
Publisher
Springer-Verlag New York, LLC
Pages
398
Format
Paperback
ISBN
9781461285434

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