Overview
This second edition of a successful title bridging toxicology and environmental chemistry adopts a unique approach that 'follows' chemicals on a molecular level, from the environment through the different uptake mechanisms into the body. Along the way, this textbook explains the different routes of degradation and metabolism of the different classes of chemicals, linking general chemical properties to their toxicological equivalents. All the chapters have been thoroughly updated and the contents significantly expanded, including new chapters on modern pesticides, food chemicals and solvents, as well as a chapter discussing the difficulties of accurate measurements of carcinogenesis in man.
The text is aimed at a wide audience ranging from pharmacologists to environmental chemists and toxicologists.
Synopsis
This second edition of a successful title bridging toxicology and environmental chemistry adopts a unique approach that ‘follows’ chemicals on a molecular level, from the environment through the different uptake mechanisms into the body, to the toxic effect. Along the way, this textbook explains the different routes of degradation and metabolism of the different classes of chemicals, linking general chemical properties to their toxicological equivalents. All the chapters have been thoroughly updated and the contents significantly expanded, including for example new chapters on pesticides, food chemicals and pharmaceuticals, as well as sections discussing endocrine disruptors and carcinogenicity assays.
The text is aimed at a wide audience ranging from pharmacologists to environmental chemists and toxicologists.
Booknews
Examines the relationships between the structures of organic compounds and their properties, and between the chemical properties and the effects on human health and the environment, for example cancer and climatic change. To help chemists predict and thereby avoid chemical hazards, Sterner (Lund University, Sweden) explains how to determine the behavior of a chemical from a simple visual inspection of the chemical structure, and how to identify the substructures and functional groups that are associated with toxicity and adverse environmental effects. Annotation c. Book News, Inc., Portland, OR (booknews.com)