Overview
"This fourth edition of the Clinical Virology Manual includes 34 chapters and two appendices, each thoroughly revised and updated by noted experts. These updates address the modernization of clinical virology and new developments in the field, with a strong emphasis on molecular diagnostics. Importantly, this new edition includes material on several recently described viruses including human metapneumovirus, West Nile virus, bocaviruses, and newer influenza viruses and adenoviruses, plus a broadened focus on papillomaviruses and polyomaviruses." Divided into two sections, this volume presents essential information for clinicians and laboratory virologists alike. Section I details laboratory procedures for detecting and handling viruses, from specimen requirements and quality assurance to virus detection and identification, from the fundamentals through the latest molecular methods. Section II presents the most current knowledge on the wide range of specific viral pathogens. Finally, two appendices provide valuable and up-to-date information on services provided by federal and state public health virology laboratories.Synopsis
"This fourth edition of the Clinical Virology Manual includes 34 chapters and two appendices, each thoroughly revised and updated by noted experts. These updates address the modernization of clinical virology and new developments in the field, with a strong emphasis on molecular diagnostics. Importantly, this new edition includes material on several recently described viruses including human metapneumovirus, West Nile virus, bocaviruses, and newer influenza viruses and adenoviruses, plus a broadened focus on papillomaviruses and polyomaviruses." Divided into two sections, this volume presents essential information for clinicians and laboratory virologists alike. Section I details laboratory procedures for detecting and handling viruses, from specimen requirements and quality assurance to virus detection and identification, from the fundamentals through the latest molecular methods. Section II presents the most current knowledge on the wide range of specific viral pathogens. Finally, two appendices provide valuable and up-to-date information on services provided by federal and state public health virology laboratories.
Doody Review Services
Reviewer:Rebecca T. Horvat, PhD, D(ABMM)(University of Kansas Medical Center)
Description:This book describes the variety of viruses that infect humans and the diagnostic assays used to detect them. The previous edition was published in 2000.
Purpose:Much has changed during the nine years since the last edition, and the major purpose is to provide an update. This is important at a time when new viruses are emerging and spreading quickly. This book will become an important resource for those engaged in clinical virology.
Audience:Physician and laboratory scientists are the intended audience. The authors are all recognized virologists who address practical issues in each chapter.
Features:The first section of the book describes very detailed methods used to detect and grow viral pathogens. Chapters set out culture techniques used to grow various viral strains and detection methods including electron microscopy and fluorescence. This section also includes methods to detect human immune responses to viral infections and newer methods that monitor viral nucleic acid in infected patients. The next section, the largest, describes viral agents that cause specific diseases such as respiratory disease, childhood illnesses, and hepatitis. It also includes chapters on groups of viruses such as arboviruses, which are not always closely related but have a common life cycle, and herpes viruses, which are related and exhibit unique abilities to integrate into the host cell genome and reactivate with viral production periodically. The last section includes reference laboratories and contact information.
Assessment:This is a well written and designed book. This updated version is needed in light of the large number of new viral pathogens that have been discovered over the past 10 years. It should be a required reference for any clinical laboratory.
Editorials
From The Critics
Reviewer: Rebecca T. Horvat, PhD, D(ABMM)(University of Kansas Medical Center)Description: This book describes the variety of viruses that infect humans and the diagnostic assays used to detect them. The previous edition was published in 2000.
Purpose: Much has changed during the nine years since the last edition, and the major purpose is to provide an update. This is important at a time when new viruses are emerging and spreading quickly. This book will become an important resource for those engaged in clinical virology.
Audience: Physician and laboratory scientists are the intended audience. The authors are all recognized virologists who address practical issues in each chapter.
Features: The first section of the book describes very detailed methods used to detect and grow viral pathogens. Chapters set out culture techniques used to grow various viral strains and detection methods including electron microscopy and fluorescence. This section also includes methods to detect human immune responses to viral infections and newer methods that monitor viral nucleic acid in infected patients. The next section, the largest, describes viral agents that cause specific diseases such as respiratory disease, childhood illnesses, and hepatitis. It also includes chapters on groups of viruses such as arboviruses, which are not always closely related but have a common life cycle, and herpes viruses, which are related and exhibit unique abilities to integrate into the host cell genome and reactivate with viral production periodically. The last section includes reference laboratories and contact information.
Assessment: This is a well written and designed book. This updated version is needed in light of the large number of new viral pathogens that have been discovered over the past 10 years. It should be a required reference for any clinical laboratory.