Cytogenetics of Mammalian Embryonic Development

Chromosome anomalies are a major cause of embryonic mortality as well as of mental and physical defects, but until very recently it has been almost impossible to understand the underlying causal mechanisms linking chromosomes and development. In this book, two eminent biomedical scientists explain how laboratory experiments with mice are finally revealing the molecular basis of gene expression in early development. Comprehensive and up-to-date, Dyban and Baranov's work is the first attempt to review the whole field by bringing together the important research being done in the United States, the Soviet Union, Britain, and Germany.