Physiology, Medical Research, Orthopedics, Physiology - Musculoskeletal System, Anatomy, Embryology, Biology - Developmental
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Overview
Sarcoplasmic reticulum is a form of endoplasmic reticulum found in large quantities in mature muscle cells. Anthony Martonosi presents general information about the development and function of the sarcoplasmic reticulum within a framework of contemporary research on the molecular biology of biosynthetic and signaling processes. Focusing on the development of the sarcoplasmic reticulum, Martonosi demonstrates the regulatory functions that control the production of its molecular components and investigates the interaction of these lipid and protein molecules with the myogenic, neurogenic and hormonal stimuli present in developing muscle cells. Martonosi provides extensive experimental support throughout the book.The book contains predominantly black-and-white illustrations, with some color illustrations.
Editorials
John Gergely
There is a wealth of information in this book touching on problems of the development of the sarcoplasmic reticulum and of other elements relevant to excitation contraction coupling.From The Critics
Reviewer:Eugene A Davidson, PhD(Georgetown University School of Medicine)Description:This book has two separate sections. The first is an 18-chapter compilation of work on muscle development and the second is a nearly 200-page bibliography. As a reference, the latter is strong motivation for investigators to acquire this book.
Purpose:The purpose is to serve as a review of information on the sarcoplasmic reticulum.
Audience:Investigators and fellows are the intended audience.
Features:The initial chapter serves as an overview of muscle development and is followed by discussions of protein expression and degradation, and the role of phospholipids. Formation of the excitation-contraction apparatus is reviewed followed by chapters on channels. Calcium and its role in muscle development and function is discussed from a variety of aspects including regulation of synthesis of several proteins, signal transduction and the acetylcholine receptor.
Assessment:Each of the topics is covered in detail, often with critical analysis of published data. In that regard, this book makes a valuable contribution. A minor caveat is that because of the exhaustive bibliography, the text is constantly interrupted by literature citations. This makes reading somewhat disconnected, but the value of the bibliography far outweighs this inconvenience. This book is highly recommended for all investigators working with muscle.
3 Stars from Doody
Book Details
Published
August 7, 2000
Publisher
Taylor & Francis, Inc.
Pages
632
ISBN
9780203305010