Every Patient Tells a Story: Medical Mysteries and the Art of Diagnosis

A healthy young man suddenly loses his memory-unable to remember the events of each passing hour. Two patients, diagnosed with Lyme disease, improve after antibiotic treatment-only to have their symptoms mysteriously return. A young woman lies dying in the ICU-bleeding, jaundiced, incoherent-and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us to the bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.

In her first book, internist and New York Times columnist Sanders discusses how doctors deal with diagnostic dilemmas. Unlike Berton Roueché in his books of medical puzzles, Sanders not only collects difficult cases, she reflects on what each means for both patient and struggling physician. A man arrives at the hospital, delirious, his kidneys failing. Batteries of tests are unrevealing, but he quickly recovers after a resident extracts two quarts of urine. An abdominal exam would have detected the patient's obstructed, grossly swollen bladder. The author then ponders the neglect of the physical exam, by today's physicians, enamored with high-tech tests that sometimes reveal less than a simple exam. Another patient, frustrated at her doctor's failure to diagnose her fever and rash, googles her symptoms and finds the correct answer. Sanders uses this case to explain how computers can help in diagnoses (Google is not bad, she says, but better programs exist). Readers who enjoy dramatic stories of doctors fighting disease will get their fill, and they will also encounter thoughtful essays on how doctors think and go about their work, and how they might do it better. (Apr. 14)

Lisa Sanders, M.D. is an Assistant Clinical Professor at the Yale University School of Medicine and a clinician educator in Yale’s Primary Care Internal Medicine Residency program. Dr. Sanders writes the popular “Diagnosis” column, which appears monthly in The New York Times Magazine.

Her column was the inspiration for the acclaimed Fox television show “House M.D.,” and she currently serves as technical advisor for the show. Although teaching about clinical reasoning and diagnostic error is her first love, much of her research and practice focus on the treatment of overweight and obese patients She is the author of The Perfect Fit Diet: How to Lose Weight, Keep it Off And Still Eat the Foods You Love.

Before entering medical school, Sanders was an Emmy Award-winning producer at CBS News, where she covered medicine and health and she also worked as a producer at ABC and NBC News. She lives in New Haven, Connecticut.