Physiology, Endocrinology & Metabolism, Cytology - Structural & Functional Aspects, Anatomy, Physiology - General & Miscellaneous, Internal Medicine, Physiology - Digestive & Excretory Systems

Extracellular Matrix

Name: Extracellular Matrix
Author: Mark A. Zern, Lola M. Reid
ISBN: 9780824788308

by Mark A. Zern, Lola M. Reid

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Overview

Describing state-of-the-art research techniques for clinicians and introducing important clinical perspectives for basic scientists, this reference examines some significant areas of investigation into the biology of the extracellular matrix and its implications in human pathophysiology.;Focusing on the liver and providing a broad survey of the latest information available, Extracellular Matrix: discusses a wide range of models and organ systems; presents pathophysiological studies emphasizing hepatic disease, particularly the development of fibrosis and cirrhosis; furnishes structure and function analyses of the major extracellular matric components, including collagens, laminin, fibronectin, and proteoglycans; delineates the mechanisms leading to increased depositions of the matrix proteins during hepatic fibrogenesis; details new therapeutic approaches to liver disease; and more.;With authoritative contributions from more than 40 leading international experts representing five countries, Extracellular Matrix should be a useful reference for all scientists interested in matrix biology, chemistry, or pathobiology, especially gastroenterologists, hepatologists, pathologists, and graduate and medical school students in these disciplines.

This book contains black-and-white illustrations.

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Booknews

The extracellular matrix is an insoluble complex of proteins and carbohydrates produced by all metazoan cells. Bridging the gulf between basic scientists and clinicians, this volume contains contributions by basic researchers, who present their information with considerations of possible clinical implications, and by clinicians, who discuss the disease processes in a manner that might stimulate new questions to be addressed by basic research. The 22 chapters are grouped within five sections: matrix chemistry and structure, extracellular matrix of the liver, pharmacology/endocrinology and therapeutics of matrix, functions, and pathogenesis. Annotation c. Book News, Inc., Portland, OR (booknews.com)