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Overview
This book covers the study of genome structure and function from primary to high order structures and gene expression in the control of cell function and cell cycle progression. The major emphasis is on a deep understanding of DNA structure and function in interphase and metaphase chromosomes. A compilation of the most up to date information from the most outstanding scientists in the field. A comprehensive textbook for all student levels.
The book contains black-and-white illustrations.
Synopsis
This book covers the study of genome structure and function from primary to high order structures and gene expression in the control of cell function and cell cycle progression. The major emphasis is on a deep understanding of DNA structure and function in interphase and metaphase chromosomes.
A compilation of the most up to date information from the most outstanding scientists in the field. A comprehensive textbook for all student levels.
Carolyn Jahn
This book is a compilation of 15 reviews written by researchers who participated in a NATO Advanced Study Institute course in June 1996. The course focused on ""Genome Structure and Function"" and covered many aspects of DNA structure, from the higher order structure of chromosomes and chromatin to the characterization of specific genes and promoters. A variety of research methods are represented from biophysical methods to cell and molecular biology. A few chapters focus on biotechnology, particularly transgenic plants. The purpose was to provide insight into the many aspects of genome study and to the current state of research in the field. The book is written for molecular and cellular biologists, most likely researchers in related areas, but also graduate students looking for information above the level of textbooks. Several chapters are written by well-known researchers who have written numerous reviews. These chapters tend to be broad in content, giving a good overview. Other chapters are very restricted in focus, for instance the characterization of viral translational enhancers for use in transgenic plants. The illustrations are black and white and of poor quality: even bar graphs are not reproduced well. The references in most cases are relevant and up-to-date. The book does not have a uniform level of presentation. The chapters that are general are similar to reviews by the same authors that are published elsewhere and readily available; the other chapters do not add sufficient general information to make the articles useful. The objective of the book is laudable, but the particular mix of reviews does not make the book a worthwhile purchase.
Editorials
From The Critics
Reviewer: Carolyn Jahn, PhD(Northwestern University Feinberg School of Medicine)Description: This book is a compilation of 15 reviews written by researchers who participated in a NATO Advanced Study Institute course in June 1996. The course focused on "Genome Structure and Function" and covered many aspects of DNA structure, from the higher order structure of chromosomes and chromatin to the characterization of specific genes and promoters. A variety of research methods are represented from biophysical methods to cell and molecular biology. A few chapters focus on biotechnology, particularly transgenic plants.
Purpose: The purpose was to provide insight into the many aspects of genome study and to the current state of research in the field.
Audience: The book is written for molecular and cellular biologists, most likely researchers in related areas, but also graduate students looking for information above the level of textbooks.
Features: Several chapters are written by well-known researchers who have written numerous reviews. These chapters tend to be broad in content, giving a good overview. Other chapters are very restricted in focus, for instance the characterization of viral translational enhancers for use in transgenic plants. The illustrations are black and white and of poor quality: even bar graphs are not reproduced well. The references in most cases are relevant and up-to-date.
Assessment: The book does not have a uniform level of presentation. The chapters that are general are similar to reviews by the same authors that are published elsewhere and readily available; the other chapters do not add sufficient general information to make the articles useful. The objective of the book is laudable, but the particular mix of reviews does not make the book a worthwhile purchase.
From The Critics
Reviewer: Carolyn Jahn, PhD(Northwestern University Feinberg School of Medicine)Description: This book is a compilation of 15 reviews written by researchers who participated in a NATO Advanced Study Institute course in June 1996. The course focused on "Genome Structure and Function" and covered many aspects of DNA structure, from the higher order structure of chromosomes and chromatin to the characterization of specific genes and promoters. A variety of research methods are represented from biophysical methods to cell and molecular biology. A few chapters focus on biotechnology, particularly transgenic plants.
Purpose: The purpose was to provide insight into the many aspects of genome study and to the current state of research in the field.
Audience: The book is written for molecular and cellular biologists, most likely researchers in related areas, but also graduate students looking for information above the level of textbooks.
Features: Several chapters are written by well-known researchers who have written numerous reviews. These chapters tend to be broad in content, giving a good overview. Other chapters are very restricted in focus, for instance the characterization of viral translational enhancers for use in transgenic plants. The illustrations are black and white and of poor quality: even bar graphs are not reproduced well. The references in most cases are relevant and up-to-date.
Assessment: The book does not have a uniform level of presentation. The chapters that are general are similar to reviews by the same authors that are published elsewhere and readily available; the other chapters do not add sufficient general information to make the articles useful. The objective of the book is laudable, but the particular mix of reviews does not make the book a worthwhile purchase.
Carolyn Jahn
This book is a compilation of 15 reviews written by researchers who participated in a NATO Advanced Study Institute course in June 1996. The course focused on ""Genome Structure and Function"" and covered many aspects of DNA structure, from the higher order structure of chromosomes and chromatin to the characterization of specific genes and promoters. A variety of research methods are represented from biophysical methods to cell and molecular biology. A few chapters focus on biotechnology, particularly transgenic plants. The purpose was to provide insight into the many aspects of genome study and to the current state of research in the field. The book is written for molecular and cellular biologists, most likely researchers in related areas, but also graduate students looking for information above the level of textbooks. Several chapters are written by well-known researchers who have written numerous reviews. These chapters tend to be broad in content, giving a good overview. Other chapters are very restricted in focus, for instance the characterization of viral translational enhancers for use in transgenic plants. The illustrations are black and white and of poor quality: even bar graphs are not reproduced well. The references in most cases are relevant and up-to-date. The book does not have a uniform level of presentation. The chapters that are general are similar to reviews by the same authors that are published elsewhere and readily available; the other chapters do not add sufficient general information to make the articles useful. The objective of the book is laudable, but the particular mix of reviews does not make the book a worthwhile purchase.Booknews
Papers from a June meeting describe DNA structure and gene expression of control of cell function and cell cycle progression, covering both structural and functional aspects, and give insight into modern problems of genome study and recent achievements in related fields of molecular and cell biology, genetic engineering, biochemistry and biophysics, oncology, and biotechnology. Emphasis is on DNA structure and function in interphase and metaphase chromosomes as revealed in biophysical and biochemical studies conducted on a range of cell systems. Other subjects include industrial utilization of recombinant DNA in agriculture and health, and novel or non-conventional instrumentation for the study of DNA, such as scanning probe microscopy, synchrotron radiation, and biosensors. Annotation c. by Book News, Inc., Portland, Or.2 Stars from Doody