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Guinea Pig Scientists: Bold Self-Experimenters in Science and Medicine by Mel Boring — book cover

Guinea Pig Scientists: Bold Self-Experimenters in Science and Medicine

by Mel Boring, Leslie Dendy, C. B. Mordan
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Overview

It was August 27, 1885. In a hospital in Lima, Peru, a student named Daniel Carrión was preparing to infect himself with a dreaded disease . . . He had a small, sharp lancet ready . . . Carrión's friends and teacher from the medical school thought it was a bad idea. They knew Carrión was eager to learn more about this mysterious disease.

But were the risks worth it?

Science and medicine from the inside out-ten engrossing stories of self-experimentation

Who are these "guinea pig scientists"? Searching for clues to some of science's and medicine's bigger (and sometimes stranger) questions, they are all the men and women who devoted their lives to help find the answers. Spanning from the 1770s to the present-and uncovering the science behind digestion, the spread of yellow fever, the development of the first heart catheter, and more-their ten stories are at once scientifically detailed and fascinatingly personal.

Synopsis

It was August 27, 1885. In a hospital in Lima, Peru, a student named Daniel Carrión was preparing to infect himself with a dreaded disease . . . He had a small, sharp lancet ready . . . Carrión's friends and teacher from the medical school thought it was a bad idea. They knew Carrión was eager to learn more about this mysterious disease.

But were the risks worth it?

Science and medicine from the inside out-ten engrossing stories of self-experimentation

Who are these "guinea pig scientists"? Searching for clues to some of science's and medicine's bigger (and sometimes stranger) questions, they are all the men and women who devoted their lives to help find the answers. Spanning from the 1770s to the present-and uncovering the science behind digestion, the spread of yellow fever, the development of the first heart catheter, and more-their ten stories are at once scientifically detailed and fascinatingly personal.

Kathleen Isaacs - Children's Literature

For hundreds of years, scientists have experimented on themselves, curious about how the human body works and what it can stand. The ten biographies in this intriguing collection portray men and women who swallowed inedible substances, exposed themselves to diseases, subjected themselves to intense heat and pressure, gas, radiation, and isolation, and injected probes into their hearts. The scientists described include Lazzaro Spallanzani, William Morton and Horace Wells, Marie and Pierre Curie, John Scott Haldane and Jack Haldane, John Paul Stapp, and Stefania Follini and others, working from the 1700s to nearly the present. Each chapter begins with a black-and-white portrait of the scientist(s) and ends with a section entitled "Now We Know." This highlights current understandings in the field of the self-experimenter, whether it be how the digestive system works, how much pressure the human body can stand, what happens to biological clocks when you are without outside time clues, or how diseases like yellow fever are transmitted and treated. Sidebars explain unfamiliar vocabulary and introduce others who worked in the field. The end matter includes an extensive bibliography for each subject, quotation sources, acknowledgements, credits for the black-and-white photographs that also illustrate each chapter, and a substantial index. In spite of the intriguing subject matter and proliferation of gory detail, the appearance of this book—with its black-and-white format, small type, and considerable heft—is serious. It may require some selling on the part of adults. This would be excellent supplementary reading for high school biology classes. 2005, Henry Holt and Company, Ages 12up.

About the Author, Mel Boring

Leslie Dendy has been teaching biology and chemistry for nearly thirty years. She is the author of Tracks, Scats, and Signs and lives with her husband in Los Alamos, New Mexico.

Mel Boring is the author of a number of nonfiction picture books, as well as a novel. He lives in Rockford, Iowa, with his family.

C. B. Mordan is the illustrator of several books for young readers, including Lost: A Story in String. He lives near Kansas City, Missouri.

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Editorials

Children's Literature

For hundreds of years, scientists have experimented on themselves, curious about how the human body works and what it can stand. The ten biographies in this intriguing collection portray men and women who swallowed inedible substances, exposed themselves to diseases, subjected themselves to intense heat and pressure, gas, radiation, and isolation, and injected probes into their hearts. The scientists described include Lazzaro Spallanzani, William Morton and Horace Wells, Marie and Pierre Curie, John Scott Haldane and Jack Haldane, John Paul Stapp, and Stefania Follini and others, working from the 1700s to nearly the present. Each chapter begins with a black-and-white portrait of the scientist(s) and ends with a section entitled "Now We Know." This highlights current understandings in the field of the self-experimenter, whether it be how the digestive system works, how much pressure the human body can stand, what happens to biological clocks when you are without outside time clues, or how diseases like yellow fever are transmitted and treated. Sidebars explain unfamiliar vocabulary and introduce others who worked in the field. The end matter includes an extensive bibliography for each subject, quotation sources, acknowledgements, credits for the black-and-white photographs that also illustrate each chapter, and a substantial index. In spite of the intriguing subject matter and proliferation of gory detail, the appearance of this book—with its black-and-white format, small type, and considerable heft—is serious. It may require some selling on the part of adults. This would be excellent supplementary reading for high school biology classes. 2005, Henry Holt and Company, Ages 12up.
—Kathleen Isaacs

School Library Journal

Gr 5 Up-Scientifically speaking, a "guinea pig" is a person who volunteers to serve as a subject in a scientific study. An easy and interesting read, this book describes 18th-century Italian scientist Lazzaro Spallanzani and his research on himself to explore digestion by swallowing food encapsulated in wooden tubes or cloth satchels and then analyzing the remains of the samples upon their exit from the intestinal tract. Gross enough to capture readers' attention, and startling enough to hold onto it, Spallanzani's story ends with a description of his discoveries and how many of his observations are still valid. Other topics describe guinea-pig scientists who tested internal body temperature in extreme heat and cold conditions, inhaled various gasses to discover one suitable for anesthetic uses (today's laughing gas), and seven more captivating narratives. Each chapter concludes with a list of facts derived from the work of these scientists, what they proposed and discovered, and what we now know about these topics. Black-and-white sketches and old photographs give these unbelievable stories a sense of realism. The book does not encourage young scientists to use themselves as guinea pigs, but these biographies are provocative with underpinnings of intrigue for discovering what is yet unknown.-Jodi Kearns, University of Akron, OH Copyright 2005 Reed Business Information.

Kirkus Reviews

This account of scientists who have used their own bodies and minds as subjects of experimentation forms a satisfyingly gruesome exploration of scientific dedication. George Fordyce explored the limits of the human ability to endure extreme heat and helped to explain why "it's not the heat; it's the humidity"; Daniel Carri-n's self-infection with the deadly verruga peruana resulted in his death and the renaming of the disease in his honor; Marie Curie's experimentation with radium killed her but led to radiation therapy. Although these men and women, and several others introduced in this fascinating tome, were often viewed as crackpots, the text makes clear that it was their willingness to suffer that has led to many significant medical advances. The text is often sprightly and delivers just the right factoids to keep up flagging interest. Mordan's clean inked portraits and details supplement archival illustrations; sidebars and chapter-ending "Now We Know" segments extend the information presented in the narrative. An introduction warns readers not to try these experiments on themselves; an author's note informs readers of their methodology and approach to source material. Solid and fascinating. (Nonfiction. 10+)

Book Details

Published
June 1, 2005
Publisher
Henry Holt and Co. (BYR)
Pages
224
Format
Hardcover
ISBN
9780805073164

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