Physiology, Infectious Diseases, Immunology, Physiology - Immune System, Sexual Health - Diseases & Disease Prevention, Dermatology, Microbiology
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Overview
An outstanding collection of state-of-the-art experimental methods for herpes virology. These procedures range from the more biological in vivo maneuvers to the purely molecular, and are described in detail by selected experts to ensure reproducibility. Most of the prools rely on the herpes simplex virus as prototype, so that it then becomes relatively easy to
extrapolate and make the necessary modifications required for application to other herpesviruses, especially members of the alpha group, such as PRV and EHV.
The book contains black-and-white illustrations.
Synopsis
Herpes Simplex Virus Protocols comprises a wide range of experimental protocols that should be especially useful to new workers in herpes virology. Hopefully, it will also provide information for those with experience in the field, as well as those embarking on techniques that are new to them. Obviously the range of topics covered cannot be comprehensive, but we have tried to provide protocols dealing with those procedures that are most widely used; and we have selected expert authors accordingly. We have also tried to cover the range from the more biological in vivo maneuvers to purely molecular procedures, taking into account the topical interest in the potential use of HSV as a therapeutic tool. In this way there should be sufficient inf- mation for most procedures the average herpes virologist is likely to require-- at least at this moment in time! Since the herpesviruses are a large family, we have largely based the protocols on the virus we know best--herpes simplex virus. With this as the prototype, it should be relatively easy to extrapolate and make the necessary modifications required for application to some of the other herpesviruses, especially members of the alpha group, such as PRV and EHV. It would have been an impossible task to include chapters covering the unique aspects of each known herpesvirus.Editorials
Jerry Lynn Taylor
This is a collection of complete procedures for basic methods used in research on herpes simplex virus. The book is designed to provide protocols to cover a wide range of topics. The procedures range from the very basic, such as propagation of the virus, to more complex protocols for genetic methods, studies on regulation of virus replication in cell culture systems, and animal models. It is intended as a reference book. Students just beginning their studies on herpes viruses will find this resource useful, as will more experienced scientists who are beginning studies with the herpes simplex virus. Herpes virologists who are initiating studies in a new aspect of the field will also find these detailed descriptions of techniques helpful. The editors have compiled individual chapters written by authorities with extensive experience using the techniques they describe. This results in detailed, complete descriptions of materials and methods. Extremely useful information on rationales, expected results, problems that may arise, and evaluation of results are also presented. Illustrations are limited, but those presented are helpful. References to historically important studies in which the methods were developed are included as well as more recent references illustrating how these protocols have been used to answer questions about the herpes simplex virus. The wisdom derived from the extensive experience of the collected contributors will be especially useful for neophyte researchers.From The Critics
Reviewer: Jerry Lynn Taylor, PhD(Medical College of Wisconsin)Description: This is a collection of complete procedures for basic methods used in research on herpes simplex virus.
Purpose: The book is designed to provide protocols to cover a wide range of topics. The procedures range from the very basic, such as propagation of the virus, to more complex protocols for genetic methods, studies on regulation of virus replication in cell culture systems, and animal models. It is intended as a reference book.
Audience: Students just beginning their studies on herpes viruses will find this resource useful, as will more experienced scientists who are beginning studies with the herpes simplex virus. Herpes virologists who are initiating studies in a new aspect of the field will also find these detailed descriptions of techniques helpful.
Features: The editors have compiled individual chapters written by authorities with extensive experience using the techniques they describe. This results in detailed, complete descriptions of materials and methods. Extremely useful information on rationales, expected results, problems that may arise, and evaluation of results are also presented. Illustrations are limited, but those presented are helpful. References to historically important studies in which the methods were developed are included as well as more recent references illustrating how these protocols have been used to answer questions about the herpes simplex virus.
Assessment: The wisdom derived from the extensive experience of the collected contributors will be especially useful for neophyte researchers.
3 Stars from Doody
Book Details
Published
November 9, 2010
Publisher
Springer-Verlag New York, LLC
Pages
432
Format
Paperback
ISBN
9781617370137