Health, Aging, Biochemistry, Clinical Medicine, Women's Health, Chemistry - Biochemistry
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Overview
In recent years hormone replacement therapy (HRT) has become the treatment of choice for women with menopausal symptoms. At the same time, biomedical research continues to generate large amounts of new data on HRT and its impact. Now as never before, gynecologists and general practitioners are in need of easily accessible information on HRT and its physiological effects.Drawing on the considerable clinical and research experience of its authors, HRT and the Endometrium discusses endometrial changes in the clinical context as well as the molecular level. The book explores techniques for endometrial evaluation in post-menopausal women on HRT, including the first analysis of histomorphometry for quantitating endometrial changes. It emphasizes the connection between postmenopausal bleeding and HRT, summarizing statistical methods for the assessment of bleeding patterns and outlining the clinical options for avoiding this complication. In addition, the authors highlight strategie s for overcoming the problem of compliance that are common with HRT.
HRT and the Endometrium is an essential reference for gynecologists, geriatric specialists, and family practitioners. With its comprehensive coverage of clinical guidelines and the underlying molecular events of the menopause, it is an important, timely guide for clinicians concerned with the management of menopausal symptoms.
Synopsis
In recent years hormone replacement therapy (HRT) has become the treatment of choice for women with menopausal symptoms. At the same time, biomedical research continues to generate large amounts of new data on HRT and its impact. Now as never before, gynecologists and general practitioners are in need of easily accessible information on HRT and its physiological effects.Drawing on the considerable clinical and research experience of its authors, HRT and the Endometrium discusses endometrial changes in the clinical context as well as the molecular level. The book explores techniques for endometrial evaluation in post-menopausal women on HRT, including the first analysis of histomorphometry for quantitating endometrial changes. It emphasizes the connection between postmenopausal bleeding and HRT, summarizing statistical methods for the assessment of bleeding patterns and outlining the clinical options for avoiding this complication. In addition, the authors highlight strategie s for overcoming the problem of compliance that are common with HRT.
HRT and the Endometrium is an essential reference for gynecologists, geriatric specialists, and family practitioners. With its comprehensive coverage of clinical guidelines and the underlying molecular events of the menopause, it is an important, timely guide for clinicians concerned with the management of menopausal symptoms.
Editorials
From The Critics
Reviewer: David A Ehrmann, M.D.(University of Chicago Medical Center)Description: This monograph is designed to provide the scientific background as well as a practical approach to management of the common clinical problems related to the effects of hormone replacemnt therapy on the uterine endometrium.
Purpose: The purpose of this book is to "provide an extract of the experience of the authors in dealing with the endometrium at both clinical and research levels." This objective is better met in the case of the former than the latter.
Audience: The book appears to be targeted to a clinical audience. The authors provide the scientific underpinnings of common practices. For example, the basis for the use of combined estrogen-progestin is discussed. A brief but useful review of techniques available to diagnose endometrial disorders is provided, including a review of the use of ultrasonography, hysteroscopy, and endometrial biopsy.
Features: The authors have approached the topic of endometrial physiology and pathophysiology by dividing the book into nine brief chapters. Each chapter is succinct with generally excellent illustrations, many of which are in color. The references are reasonably current and balanced. This is a unique book in that it is a hybrid of sorts — it is at the same time a practical manual and a resource that provides additional detail and references on the topics.
Assessment: Those in need of depth and scholarly treatises will not find this a useful monograph. However, for medical students, junior fellows, and busy practitioners, this monograph will fill the need for accurate and succinct information "on-the-fly."
From The Critics
Research and clinical work being carried out using sex steroids in conjunction with hormone replacement therapy (HRT) regimens to control dysfunctional bleeding are the subject of eight papers by four gynecologists and an epidemiologist at the U. of Leicester in the UK. An overview of current thinking on HRT is given in the introduction. Subsequent chapters detail statistical evaluation of menstrual events, the use and evaluation of menstrual diaries, the pathophysiology of dysfunctional bleeding and potential risk factors, and controversies over treatment. Annotation c. Book News, Inc., Portland, OR (booknews.com)3 Stars from Doody
Book Details
Published
June 15, 2001
Publisher
Informa Healthcare
Pages
182
Format
Hardcover
ISBN
9781850700920