Gynecology & Obstetrics, Oncology, Microscopes & Microscopy - Electron Microscopes, Immunology, Biochemistry - Hormones, Biochemistry - Receptors, Biology - Molecular Biology, Laboratory Medicine, Biochemistry - General & Miscellaneous, Anatomy, Cytology
Log in to track your reading progress.
Overview
A comprehensive review of the literature on steroid hormone receptor immuncytochemistry. It includes the development of the first monoclonal antireceptor antibody and initial procedures designed to localize steroid receptors in situ up to the present. The step-by-step instructions provide easy reading of topics such as tissue handling, processing, and interpretation. This text places particular emphasis on the studies of human material-especially mammary carcinoma. It presents specific details with chapters on estrogen and progesterone receptors in breast malignancies and benign breast disease. Each section of this outstanding book contains comprehensive photomicrographs that illustrate the most salient features discussed. Detailed graphs pertaining to theoretical particulars concerning technology and the relationship between image analysis and endocrine response are also included. This monograph is an excellent resource for all researchers concerned with hormone-dependent tissues, pathologists who have an interest in working with novel techniques for localizing steroid hormone receptors, and oncologists who must use assay results in the treatment of breast cancer.Editorials
Booknews
Deals with the detection of steroid receptors by immunocytochemistry. Heavily weighted towards estrogen and progesterone receptors on which nearly all the experimental work in the field has been done, though also reports the information that is available on glucocarticoid and androgen receptors. Pertschuk (pathology, SUNY, Health Science Center, Brooklyn) presents chapters on the historical development of the field; the literature pertaining to immunocytochemical assays in breast cancer; techniques for performing assays; the SUNY Health Science Center experience with progesterone, ERICA, and PgRICA in cancer and other diseases of the breast; the methodology and strategies of microscopic imaging; receptogram analysis; the female reproductive system; the cardiovascular tree; thyroid, pancreas, and other organs; and controversies and trends in the field. Acidic paper. Annotation c. Book News, Inc., Portland, OR (booknews.com)Book Details
Published
August 15, 1990
Publisher
CRC Press
Pages
224
Format
Hardcover
ISBN
9780849369438