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Overview
This book covers both basic elements and the state-of-the-art in applications of proteomics. The first section gives an introduction to the field, from differential approaches to functional proteomics, including yeast two-hybrid, mass spectrometry, mapping of post-translational modifications, and NMR spectroscopy. The second section offers a complete picture of industry studies in proteomics for human health and biotechnology applications. The final section addresses the future, looking at the most promising areas such as protein arrays and the integration of genomic and proteomic tools.
Synopsis
With the successful sequencing of the human genome, scientists are turning to the even greater challenge of understanding diverse processes at the molecular level. Figeys (biochemistry, microbiology, and immunology, U. of Ottawa, Canada) defines proteomics as the study through automated methods of the processes that regulate proteins. To fill a perceived gap in addressing industrial applications of proteomics, this collection of 11 chapters by international contributors from academia and pharmaceutical companies treats protonomics' key role in the development of drugs that target protein biomarkers of disease. Color plates show details of b&w microassays. Annotation ©2005 Book News, Inc., Portland, OR
Editorials
From the Publisher
"...very well written and cover[s] a wide range of methods." (The Quarterly Review of Biology, September 2005)
"...an excellent text that provides an overview of a number of industrial applications...is useful to anyone involved with proteomics based research." (Clinical Biochemistry, August 2005)