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Oncology, Endocrinology & Metabolism, Genetics, Pathology, Cytology - Structural & Functional Aspects, Pharmacology, Biology - Developmental, Oncology - Basic Science
Mitochondria and Cancer by Keshav Singh β€” book cover

Mitochondria and Cancer

by Keshav Singh (Editor), Leslie Costello (Editor)
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Overview

Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity; in molecular composition of mitochondria and mtDNA sequence; and in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer and discusses the clinical implications of mitochondrial defects in cancer. It also discusses the practicality of using these defects as unique cellular targets for novel and selective anti-cancer therapy.

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Book Details

Published
October 29, 2010
Publisher
Springer-Verlag New York, LLC
Pages
301
Format
Paperback
ISBN
9781441927385

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