Modern HPLC for Practicing Scientists

A comprehesive yet concise guide to Modern HPLC

Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers.

Topics covered include:

• HPLC operation
• Method development
• Maintenance and troubleshooting
• Modern trends in HPLC such as quick-turnaround and "greener" methods
• Regulatory aspects

While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources.

With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

A comprehesive yet concise guide to Modern HPLC

Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers.

Topics covered include:

• HPLC operation
• Method development
• Maintenance and troubleshooting
• Modern trends in HPLC such as quick-turnaround and "greener" methods
• Regulatory aspects

While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources.

With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

MICHAEL W. DONG, PhD, is a Research Director at Synomics Pharma in Wareham, Massachusetts,responsible for chromatography method development and research studies. He has been a research fellow/group leader at Purdue Pharma, a senior staff scientist at PerkinElmer, and a section head at Hoechst Celanese. He holds a BSc in chemistry from Brooklyn College and a PhD in analytical chemistry from the City University of New York Graduate Center. Dr. Dong pioneered Fast LC and has over eighty publications in chromatography and analytical chemistry. He is the coeditor of another book on pharmaceutical analysis by HPLC, published in 2005.