Physiology, Physiology - Cellular & Microorganisms, Pathology, Genetics - General and Miscellaneous, Anatomy, Cytology - Structural & Functional Aspects, Human Anatomy - General & Miscellaneous

Molecular Biology in Histopathology

Name: Molecular Biology in Histopathology
Author: John Crocker
ISBN: 9780471940937

by John Crocker

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Overview

This series is designed to bridge the gap between pure research in the biomedical sciences and its practical application in clinical medicine. The objective is to promote the understanding of the molecular basis of human physiology and disease, and new techniques for diagnosis and treatment. Primarily intended for graduate students of medicine, the books will also be of use to molecular biologists, biochemists, physiologists, pharmacologists and biotechnologists, as well as medical practitioners and technicians who seek to update their knowledge. Edited by John Crocker East Birmingham (Heartlands) Hospital, Birmingham, UK Molecular biology has transformed the practice of histopathology in recent years. Knowledge of the molecular organization of the cell has led to the development of powerful new techniques which bring greater accuracy and objectivity to the diagnosis, prognosis and management of many diseases, and to the study of pathological states. This book describes the molecular techniques available and other techniques related to the molecular biology of the cell and provides an overview of how they can be applied. It is aimed not only at histopathologists in training but also at clinicians and biologists studying for masters’ and postdoctoral qualifications.

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An introduction to the currently available molecular techniques in histology and an account of the molecular basis of certain phenomena of importance in everyday histopathology. Eight chapters address in situ hybridization in relation to infectious agents; genetic analysis of malignancy in histopathological material using filter and in situ hybridization; the polymerase chain reaction as a tool for the histopathologist; interphase cytogenetics; DNA flow cytometry; molecular and immunological aspects of cell proliferation; interphase nucleolar organizer regions; and apoptosis--molecular aspects and pathological perspective. Annotation c. Book News, Inc., Portland, OR booknews.com