Physiology, Radiology & Diagnostic Imaging, Physiology - General & Miscellaneous, Cardiology, Physiology - Cardiovascular & Respiratory Systems
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Overview
A convenient guide of easily accessible information on the mechanisms of myocardial repolarization and related clinical issues.This book provides a unique collection of contributions by prominent cardiologists on the current knowledge of the mechanisms of arrhythmias, the molecular and genetic bases of noninvasive electrocardiologic diagnosis, and other related clinical issues. In addition to mechanistic aspects, recent developments in the diagnosis of arrhythmias using newly recognized markers (QT dispersion, T-wave alternans, etc.) and their clinical importance are addressed in an easily accessible manner by world-renowned authors.
The book is a quick-reference for practicing cardiologists and electrophysiologists, those in training, and others who work in the field of arrhythmology.
Editorials
From The Critics
Reviewer: John F. Moran, MD(Loyola University Stritch School of Medicine)Description: This book about myocardial repolarization and the QT interval is divided into five sections that cover the cellular molecular mechanisms of myocardial repolarization, clinical measurements of the QT interval, and the long QT syndrome, both congenital and acquired.
Purpose: The purpose is to provide an up-to-date reference for cardiologists and electrophysiologists, as well as clinical pharmacologists. The book certainly meets these objectives.
Audience: All electrophysiology practitioners would be interested in this, as well as all students of arrhythmology. The multiauthored book is written by an international cadre of 56 clinical and basic electrophysiologists.
Features: The book starts with the history of the electrocardiogram and arrhythmias, as well as the development of the long QT syndrome and torsades des pointes. The chapters in the first section begin with the physiology of repolarization going into regional differences in repolarization, as well as current such as Ito and Iks, as well as the cycle lengths and the effects of antiarrhythmic drugs on these currents. The importance of myocardial stretch on repolarization and how stretch activates ion channels is discussed. The QT interval itself is divided into QT dynamicity and QT adaptation. The greater value of QT/RR relationship and the heart rate and circadian modulations are described. The importance of T wave alternans and its relationship to cardiac arrhythmias and prognosis are reviewed. The long QT syndrome and its molecular basis, as well as genotype and phenotype correlations, are developed over five chapters. The chapters on the different electrophysiologic mechanisms of re-entrant, the Brudada syndrome, and drug interactions via the P450 enzyme system are particularly interesting.
Assessment: The book is very well referenced and many chapters have more than 100 citations. There are many tables and drawings, which is particularly important in the section on electrophysiologic mechanisms of re-entry. The book succeeds in its purpose of providing a reference on this very important area of electrocardiology.
4 Stars! from Doody
Book Details
Published
October 18, 2001
Publisher
Armonk, NY : Futura Pub., c2001.
Pages
402
Format
Hardcover
ISBN
9780879934774