Books.org participates in affiliate programs including Bookshop.org and the Amazon Services LLC Associates Program. We may earn a commission from qualifying purchases made through links on this page, at no additional cost to you.
Overview
Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.
Synopsis
Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.Editorials
From The Critics
Reviewer: Celso Agner, MD, MS, MSc(Michigan Neurology Partners)Description: The progress in research on neural stem cells is promoting the development of new ideas in surgical applications for management of neurodegenerative diseases. This book addresses current research protocols for neural stem cells and future applications for each of the protocols described.
Purpose: The purpose is to address research protocols and possible future applications of neural stem cells in clinical practice. The author has met the objectives.
Audience: The audience is primarily neuroscientists, neurologists, and neurosurgeons who, looking for novel modalities of treatment of their patients, may envision in this research an opportunity for better disease management. The authors are certainly credible authorities in the field.
Features: The 64 authors contribute 16 chapters in this book. Starting from the basic aspects of cell culturing, this book emphasizes the different available research protocols that are currently being used for possible management of neurological degenerative diseases. In addition, molecular mechanisms of interaction are always explained whenever necessary. There is not much discussion of the possible surgical applications of neural stem cells, as most authors are from the clinical or basic science arena.
Assessment: This book is a perfect purchase for neurologists and neuroscientists. Neurosurgeons with a basic science interest would also find this a useful acquisition.
3 Stars from Doody