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Synopsis
Modulation of vesicular glutamate release during anoxia/Batten disease, etc.
Booknews
The 54 papers delve into how the selective vulnerability to injury of different neuronal cells types is related to their function in transport, binding, and responses for excitory amino acids and other neurotransmitters; the role of amyloid proteins and other molecular and genetic risk factors in neurodegeneration; how altered cerebral-energy and amino-acid metabolism and protein synthesis predispose the central nervous system to injury by closely associated mechanisms; the roles of free radicals and oxidative stress in cellular injury and death; how calcium transport and calcium-dependent enzymes and regulatory proteins either inhibit or exacerbate irreversible neuronal injury, and neuronal growth regulation and apoptic cell death. Reproduced from typescripts. Annotation c. Book News, Inc., Portland, OR (booknews.com)