Pharmaceutical Gene Therapy Systems

This volume examines the advantages and limitations of the major gene delivery systems and offers guidelines to select the most appropriate viral or synthetic delivery system for specific therapeutic applications. International scientists discuss advances in gene therapy for facing the challenges of developing better therapeutic genes for treatment of cancer and cardiovascular, pulmonary, and infectious diseases. They review the history and development of gene therapy pharmaceuticals, assets and limitations of viral and nonviral transfer technologies, studies of pre-clinical/clinical applications, and new directions such as artificial chromosomes.