Books.org participates in affiliate programs including Bookshop.org and the Amazon Services LLC Associates Program. We may earn a commission from qualifying purchases made through links on this page, at no additional cost to you.
Overview
Based on a training course developed by Dr. Joseph T. Piechocki and other experts in this field whose contributions appear in this book for two International Meetings on the Photostability of Drugs and Drug Products, this text clarifies the guidelines set by the International Conference on Harmonization (ICH) and provides a comprehensive background in the scientific principles involved in photostability testing. Presenting the advantages and disadvantages of various procedures so the reader can select and utilize the most appropriate technique best-suited to their needs, this source includes references to current literature in the field and offers an opinion on future opportunities and challenges.
Editorials
From The Critics
Reviewer: Rahmat M Talukder, PhD (Pharmaceu, BS in Pharmacy(West Coast University School of Pharmacy)Description: This book covers the principles and applications of photostabilization techniques, which can be applied to solve problems associated with stability issues in pharmaceutical formulations, chemicals, and clinical disciplines.
Purpose: The purpose is to provide readers with a basic understanding of the principles and applications of photostabilization techniques. These objectives are relevant for pharmaceutical product development and the authors have achieved their goals.
Audience: "The authors seem to have targeted pharmaceutical scientists and anyone involved with new drug development, production, and control in the pharmaceutical industry would find this book useful. In addition, graduate students, faculty, and those at regulatory agencies actively involved in pharmaceutical quality control will benefit. Professors Thoma, Moore, and Asker have made significant contributions to this field. The scientists such as Drs. Piechocki, Harmon, Bowen, and others are well versed in this subject. "
Features: The book covers the basic principles of photostability testing, kinetics and mechanisms of photochemical reactions, available analytical methods for investigating photodegradation and photostabilization. A brief discussion of the terminology associated with this technology is helpful for readers. The chapter on photostability in clinical practice offers an intriguing discussion for clinicians as well as those in regulatory agencies, because there are no current specific guidelines on photoprotections for extemporaneous preparations. Further, the book discusses the various sources of light, filters, photostability testing chambers, and stability systems for pharmaceutical applications. Above all, it covers the relevant aspects of ICH Guidelines pertaining to photostabilization and testing. The print quality of reproductions could be better.
Assessment: "Extensive work examples are presented, based primarily on literature searches and the authors' experience in photostability research and education in academia and industry. Contributing authors have given a superior account of the pertinent issues of pharmaceutical photostability. "