Polymorphism in Molecular Crystals

Polymorphism—the multiplicity of structures or forms—is a term that is used in many disciplines. In chemistry it refers to the existence of more than one crystal structure for a particular chemical substance. The properties of a substance are determined by its composition and by its structure. In the last two decades, there has been a sharp rise in the interest in olymorphic systems, as an intrinsically interesting phenomenon, and as an increasingly important component in the development and marketing of a variety of materials based on organic molecule (e.g. pharmaceuticals, dyes and pigments, explosives etc). This book summarizes and brings up to date the current knowledge and understanding of polymorphism of molecular crystals, and concentrates it in one comprehensive source. The book will be invaluable reference for students, researchers, and professionals in the field.

Bernstein (chemistry, Ben-Gurion U. of the Negev) presents a comprehensive text and sourcebook on the polymorphism of molecular crystals for practitioners and advanced students in disciplines concerned with the organic solid state. Chapters include historical background; controlling polymorphic form; analytical techniques for studying and characterizing polymorphs; structure-property relations; polymorphism of pharmaceuticals, dyes, pigments, and high-energy materials; and polymorphism and patents. Annotation (c)2003 Book News, Inc., Portland, OR

Joel Bernstein is a professor of chemistry at Ben-Gurion Univeristy of the Negev