Refractory Depression

Booknews

Two dozen papers trace threads through the maze of questions surrounding patients whose depression does not respond to therapy, and who therefore contribute substantially to physicians' cases of morbidity and attempted and accomplished suicide. Underlying the confusion is the uncertainty whether there is a species of therapy- resistant depression, or whether diagnostic and therapeutic procedures can improve beyond the current 70% success rate. Annotation c. Book News, Inc., Portland, OR (booknews.com)