Satiation: From Gut to Brain

This volume presents the first detailed account of the neurobiological mechanisms of satiation. The ten chapters of the book detail the neural, endocrine, and cellular underpinnings of the process. Authors expert in different aspects of satiation have compiled a critical overview of recent advances and current problems in this field. Recent scientific evidence has revealed that food stimuli activate satiation before the actual absorption of digested food—a significant change to the traditional perspective that satiation depends on the post-absorptive repletion of metabolic fuels. The inclusion of a chapter on the satiation of alcohol is unique in a book on food intake, and shows the convergence of ideas on satiation in these two areas. Comprehensive in scope and accessible to a wide array of advanced students and professionals, Satiation: From Gut to Brain is an authoritative and up-to-date review of every aspect of this important physiological process. Although intended primarily for neuroscientists, nutritionists, and psychobiologists, the book will also be useful for physiologists, pharmacologists, and psychologists concerned with eating and its disorders.

The book contains black-and-white illustrations.

This volume presents the first detailed account of the neurobiological mechanisms of satiation. The ten chapters of the book detail the neural, endocrine, and cellular underpinnings of the process. Authors expert in different aspects of satiation have compiled a critical overview of recent advances and current problems in this field. Recent scientific evidence has revealed that food stimuli activate satiation before the actual absorption of digested food—a significant change to the traditional perspective that satiation depends on the post-absorptive repletion of metabolic fuels. The inclusion of a chapter on the satiation of alcohol is unique in a book on food intake, and shows the convergence of ideas on satiation in these two areas. Comprehensive in scope and accessible to a wide array of advanced students and professionals, Satiation: From Gut to Brain is an authoritative and up-to-date review of every aspect of this important physiological process. Although intended primarily for neuroscientists, nutritionists, and psychobiologists, the book will also be useful for physiologists, pharmacologists, and psychologists concerned with eating and its disorders.

Michael Easton

This book reviews the fundamental biological issues regarding how the ingestion of food results in satiation. The majority of the text is written by individuals from the Edward W. Bourne Behavioral Research Laboratory. It provides a critical review of the recent progress and problems in the scientific analysis of satiation. It looks at the development of ideas and techniques from molecular, cellular, endocrine, neural, and behavioral biology in this area. This is a highly technical publication written for individuals involved in research in this area or individuals interested in the pathophysiology of satiety. The editor and chapter contributors are experts in this area. The text is reasonably illustrated with helpful tables and charts. The references are extensive, relevant, and up-to-date. Although this book does not provide a comprehensive account of the control of food intake, it is the first to deal with the fundamental topic of satiation in a systematic and critical way. It proceeds from behavioral analysis through system physiology to cellular and molecular mechanisms, leading to increasingly detailed information about the normal structure and mechanism of satiation. It will hopefully facilitate a better understanding of hyperphagia in obesity and eating disorders.

Gerard P. Smith, M.D., is Professor of Psychiatry (Behavioral Neuroscience) at Cornell University Medical College and Director of the Edward W. Bourne Behavioral Research Laboratory at the New York Hospital-Cornell Medical Center.