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Synopsis
Alma, the narrator of Saving the World, discovers a small historical footnote while doing research for a novel: In 1803, a Spanish doctor crossed the Atlantic with twenty-two orphan boys—live carriers of the smallpox vaccine—to inoculate the population of Spain's American colonies. Accompanying them on the two-year voyage was a mysterious woman, Isabel Sendales y Gómez, the rectoress of the orphanage. Captivated by Isabe'’s courage, Alma decides to tell the grueling story of their journey.
Meanwhile, Alma's husband, working with an organization committed to eradicating AIDS in developing countries, travels to the Dominican Republic. When his life is threatened, it is Isabel's strength and resolve that arouse Alma's unexpectedly heroic action.
This novel within a novel presents the radiant stories of two women swept up in campaigns against the scourges of their day.
The Washington Post - Diana Gabaldon
This story could easily have been a black-and-white polemic, but isn't. It's subtle, nuanced and deeply compassionate; it acknowledges the basic messiness of life, yet its bleakness is redeemed by the humanity of the characters, virtually all of whom are deeply troubled in one way or another. If Alvarez doesn't ask easy questions, she doesn't settle for easy answers, either. She steadfastly avoids religion in the modern story, while acknowledging it, of necessity, in the historical narrative (and acknowledging, too, that religion is no more pure than commerce).