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Overview
Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.
Guide to data acquisition & analysis/electronic design of the patch clamp/the giant membrane patch/etc.
Synopsis
Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.
Booknews
The single-channel recording technique has reached the status of a routine method, and the view that conductance changes in biological membranes are caused by the openings and closings of ion channels is now almost universally accepted. This volume contains 22 chapters in four parts: introduction to patch clamping; methods; analysis; and "classics." There is also an appendix on improved patch-clamp techniques for high-resolution current recording from cells and cell- free membrane patches. The first edition was published in 1983. Annotation c. Book News, Inc., Portland, OR (booknews.com)