Overview
Stressing a structure-function approach, this multidisciplinary reference presents a detailed overview of the biological, chemical, physical, molecular and genetic tools and techniques utilized in the study of the skin barrier. It illustrates the impact of irritative skin reactions, as well as genetic and immune-mediated disease on hair and nail composition and formation.Synopsis
Stressing a structure-function approach, this multidisciplinary reference presents a detailed overview of the biological, chemical, physical, molecular and genetic tools and techniques utilized in the study of the skin barrier. It illustrates the impact of irritative skin reactions, as well as genetic and immune-mediated disease on hair and nail composition and formation.
Doody Review Services
Reviewer:Patricia Wong, MD(Stanford University Medical Center)
Description:The book is written by, for the most part, PhDs and is intended for researchers studying skin, hair, and nails. Current knowledge on skin embryology, skin barrier differences among us, hippos, birds, composition of stratum corneum, lipid composition and structure, and the study methods (small and wide angle X-ray diffraction, electron diffraction) are discussed in molecular detail with accompanying electron micrographs. The last half of the book focuses on underlying disrupted biochemical and molecular function and structure of the skin as seen in irritant and contact dermatitis.
Purpose:The purpose of the book is to synthesize the current knowledge base of basic science research on skin, hair, and nails and discuss similarities and differences among the three entities.
Audience:The audience is researchers in the field.
Features:I particularly enjoyed the chapters on hair pigmentation and the underlying mechanisms of graying and whitening of the hair as a normal biological phenomenon. The idea that the mealnogenetic clock may be influenced by accumulated oxidative stress causing damage to the antioxidant mechanisms is very interesting. It is the authors' intentions that the information in their book will stimulate and direct further research on human integument.
Assessment:This is a very strong basic science book that will be useful for those researchers studying hair, skin, and nails.
Editorials
From The Critics
Reviewer: Patricia Wong, MD(Stanford University Medical Center)Description: "The book is written by, for the most part, PhDs and is intended for researchers studying skin, hair, and nails. Current knowledge on skin embryology, skin barrier differences among us, hippos, birds, composition of stratum corneum, lipid composition and structure, and the study methods (small and wide angle X-ray diffraction, electron diffraction) are discussed in molecular detail with accompanying electron micrographs. The last half of the book focuses on underlying disrupted biochemical and molecular function and structure of the skin as seen in irritant and contact dermatitis. "
Purpose: The purpose of the book is to synthesize the current knowledge base of basic science research on skin, hair, and nails and discuss similarities and differences among the three entities.
Audience: The audience is researchers in the field.
Features: I particularly enjoyed the chapters on hair pigmentation and the underlying mechanisms of graying and whitening of the hair as a normal biological phenomenon. The idea that the mealnogenetic clock may be influenced by accumulated oxidative stress causing damage to the antioxidant mechanisms is very interesting. It is the authors' intentions that the information in their book will stimulate and direct further research on human integument.
Assessment: This is a very strong basic science book that will be useful for those researchers studying hair, skin, and nails.
3 Stars from Doody