Genetics - Mapping & Engineering, Genetics, Genetics - Human, Biomedicine

The Human Genome Project: Cracking the Genetic Code of Life

Name: The Human Genome Project: Cracking the Genetic Code of Life
Author: Thomas F. Lee
ISBN: 9780306439650

by Thomas F. Lee

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Overview

This is a study of genetic mapping. The first six chapters address "molecular biology in a historical framework. . . . Mapping and various kinds ofmaps (genetic, physical, sequence) are discussed. . . . (Genetic disease), diagnosis, and therapy, constitute Chapter 8. Chapter 9 outlines the evolution of the sequencing plan as it grew out of a series of conferences. . . . Chapter 10 reviews the questions involving science policy and allocation of available funds among various sectors of the biomedical research establishment. Chapter 11 covers the relationship of genome sequencing to disease, ethical issues,and social implications of genomic knowledge (medical care, employment, and insurance issues)." (Choice)

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Editorials

Publishers Weekly - Publisher's Weekly

Lee, professor of biology at St. Anselm University in N.H., here plays moderator in the clash between scientific values and the new genetics that is building around the human genome project. About three-quarters of this scientific brief on HGP is a review of the history of molecular biology; the book is akin to a rapid zoom through an electron microscope lens focused on our genes. At the end of this biology-text treatment lies the science oracle's dilemma: Given that biologists can now translate the genetic code into understandable terms and sometimes manipulate it, should they? Lee offers the general reader an outline of the science-policy stakes of HGP, noting that HGP is a protean issue, assuming the controversial character of health insurance policy, science ethics, etc. Those interested in following the development of HGP would do well to start with this earnest introduction. (Oct.)