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Overview
Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulatory approval.
Synopsis
In this update of Transdermal drug delivery: developmental issues and research initiatives, Guy (U. of Geneva, U. of Lyon) and Hadgradt (U. of Greenwich, Chatham, UK) note that this edition reflects renewed interest in this drug administration route due to further knowledge and innovations in compounds for transcending the barrier properties of the skin. In this reference volume of 11 contributions providing a state-of-the-field snapshot of advances and continuing challenges, international contributors discuss mathematical models, methods (including minimally invasive ones), and in vitro studies of dermal and transdermal drug delivery. Regulatory issues are also discussed. Though the date of the first edition is not given, it is noted that it was compiled in the late 1980s. Annotation c. Book News, Inc., Portland, OR