Transgenic Models in Endocrinology
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Overview
Transgenic Models in Endocrinology is a fitting addition to the Endocrine Updates series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Current advances in this rapidly evolving area of endocrinology make this a timely and important update for improving our understanding of transgenic models. Transgenic Models in Endocrinology continues the standard of excellence as the thirteenth volume in this series of topical updates.
Synopsis
Transgenic Models in Endocrinology is a fitting addition to the Endocrine Updates series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Current advances in this rapidly evolving area of endocrinology make this a timely and important update for improving our understanding of transgenic models. Transgenic Models in Endocrinology continues the standard of excellence as the thirteenth volume in this series of topical updates.
Doody Review Services
Reviewer:Roy E. Weiss, MD, PhD(University of Chicago Medical Center)
Description:The last 15 years has seen a revolution in the way in which we understand endocrine systems and at the forefront of these breakthroughs has been transgenic models. This book, another in the Endocrine Update series, reviews the knowledge gained from these animals in understanding the molecular basis of endocrine physiology.
Purpose:It is intended to relfect a multidisciplinary approach to transgenic animals in endocrinology bringing together molecular biologists and endocrine physiologists to write about the what we have learned from these important models. Until this month (when another book with an almost identical title appeared), there has been no book that has reviewed the important breakthroughs in our knowledge in endocrinology as a whole. The editor has assembled a distinguished list of authors on both sides of the Atlantic who have more than met the objectives.
Audience:The book is clearly written and would be useful to students of endocrinology in all stages of their careers, from beginining fellows and postdoctoral fellows to the more seasoned basic scientist and clinical scientists. The authors are world class scientists who review, for the most part, their own work.
Features:The title should not mislead the reader that this is a "how to" laboratory manual as that is not the intent of the book. The book is divided into 10 chapters. The first chapter actually deals with transgenic rats, a refreshing review of this very specialized area. The other chapters discuss knock out mouse models and transgenic mice also with viral vectors. Topics covered include reproductive functions, the stress axis, control of lactation, water and electrolyte balance, appetite control, and pituitary tumor therapy. I found the index to be very helpful in searching for my particular homones and factors of interest. Although it does not detract from the usefulness of the book, there is little comment on thyroid hormone action. There is a section of nicely done color plates.
Assessment:This month another book, Transgenics in Endocrinology edited by Matzuk, Brown and Kumar (Humana Press, 2001) also appeared and one would be remiss in not trying to compare these two books. As the titles imply, there is significant overlap of topics between these two excellent books. The book by Matzuk et al., with 20 chapters, is twice as long as this book. Several areas covered by Matzuk et al. that are not covered by Castro are skeletal biology, prostate cancer, and steroidogenesis. The Matzuk is more comprehensive, so if one could only buy one book, Castro's may not seem the wisest choice, unless one had a specific interest in neuroendocrinology.
Editorials
From The Critics
Reviewer: Roy E. Weiss, MD, PhD(University of Chicago Medical Center)Description: The last 15 years has seen a revolution in the way in which we understand endocrine systems and at the forefront of these breakthroughs has been transgenic models. This book, another in the Endocrine Update series, reviews the knowledge gained from these animals in understanding the molecular basis of endocrine physiology.
Purpose: It is intended to relfect a multidisciplinary approach to transgenic animals in endocrinology bringing together molecular biologists and endocrine physiologists to write about the what we have learned from these important models. Until this month (when another book with an almost identical title appeared), there has been no book that has reviewed the important breakthroughs in our knowledge in endocrinology as a whole. The editor has assembled a distinguished list of authors on both sides of the Atlantic who have more than met the objectives.
Audience: The book is clearly written and would be useful to students of endocrinology in all stages of their careers, from beginining fellows and postdoctoral fellows to the more seasoned basic scientist and clinical scientists. The authors are world class scientists who review, for the most part, their own work.
Features: The title should not mislead the reader that this is a "how to" laboratory manual as that is not the intent of the book. The book is divided into 10 chapters. The first chapter actually deals with transgenic rats, a refreshing review of this very specialized area. The other chapters discuss knock out mouse models and transgenic mice also with viral vectors. Topics covered include reproductive functions, the stress axis, control of lactation, water and electrolyte balance, appetite control, and pituitary tumor therapy. I found the index to be very helpful in searching for my particular homones and factors of interest. Although it does not detract from the usefulness of the book, there is little comment on thyroid hormone action. There is a section of nicely done color plates.
Assessment: This month another book, Transgenics in Endocrinology edited by Matzuk, Brown and Kumar (Humana Press, 2001) also appeared and one would be remiss in not trying to compare these two books. As the titles imply, there is significant overlap of topics between these two excellent books. The book by Matzuk et al., with 20 chapters, is twice as long as this book. Several areas covered by Matzuk et al. that are not covered by Castro are skeletal biology, prostate cancer, and steroidogenesis. The Matzuk is more comprehensive, so if one could only buy one book, Castro's may not seem the wisest choice, unless one had a specific interest in neuroendocrinology.
3 Stars from Doody