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Synopsis
New and exciting concepts in the fields of adrenal physiology and pathophysiology have been emerging almost exponentially, producing a tremendous influx of new knowledge. In Adrenal Disorders, a panel of distinguished physicians and researchers-many active contributors to the discoveries-select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. A focused review of the molecular and cellular biology of the adrenal cortices medullae, coupled with a discussion of the secretion and metabolism of adrenal products, provide a sound physiological foundation for understanding the new approaches to adrenal disease.
Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.
Doody Review Services
Reviewer:Roy E. Weiss, MD, PhD(University of Chicago Medical Center)
Description:This is an up-to-date book on the adrenal gland encompassing the latest information on the physiology and diseases. The first part of the book deals with new developments including ontogeny, steroidogenesis, and adrenal zonation as well as pharmacology including the adrenal medulla. The second part details diseases of the adrenal glands.
Purpose:The purpose is to gather the newest information available on the adrenal gland and its hormones into a clinically relevant test. Although there are several textbooks of endocrinology that cover the adrenal gland, this book is unique in its devotion solely to the adrenal gland. This allows for more detailed discussion of topics only covered in passing in the larger endocrine textbooks.
Audience:This book, authored by the experts in the field, is written in a clear manner and despite the multiple authors, is quite uniform in its style, a credit to the editors. It is an important book to be read by clinical endocrinologists and researchers in the field of adrenal hormones. Although you will not find one patient photograph in the book, the importance for clinicians is that the book presents the latest information in molecular medicine and relates it to the physiology.
Features:The book is divided into two broad sections, physiology and pathophysiology. The description of genes involved in glucocorticoid hormonogenesis, disposal, and action are beautifully done. There are no fancy color plates, but the book is worth the price for the clear descriptions and very good line drawings. The chapter on the Desmopressin test is somewhat out of place and the chapter on congenital adrenal hyperplasia is somewhat superficial, compared to the detail covered in the other chapters, and should have been more inclusive of additional defects.
Assessment:This is a unique book in the excellent series Contemporary Endocrinology. This should be on the bookshelf, or at least available, to endocrinologists and endocrine fellows in training. It will clarify many issues in the evaluation and treatment of patients with adrenal disorders.