Psychiatry - General & Miscellaneous, Physiological Psychology, Psychopathology - General & Miscellaneous, Physiology - Nervous System, Neurophysiology

Biological Psychiatry

Name: Biological Psychiatry
Author: Michael R. Trimble
ISBN: 9780470975886

by Michael R. Trimble

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Overview

This book provides an authoritative summary of the current status of the field of biological psychiatry, integrating material from the basic neuroscience investigations and clinical case studies. It offers a chapter on pharmacotherapy which outlines current consensus in the field. It contains material on such fast-moving areas as neuroimaging, panic and obsessive-compulsive disorders, as well as reports of major developments in schizophrenia, epilepsy, and Alzheimer's disease. It bridges the gap between research and clinical application.

The book contains black-and-white illustrations.

About the Author, Michael R. Trimble

Professor Trimble was for many years Professor of Behavioural Neurology and Consultant Physician to the Department of Psychological Medicine at the National Hospital Queen Square, London. He now holds emeritus status at the above institutions. He studied general medicine, obtaining membership of the Royal College of Physicians before going to the National Hospital Queen Square and then the Maudsley Hospital to advance his training in neurology and psychiatry. Following an internship in psychiatry at the Johns Hopkins Hospital, Baltimore, he returned to the National Hospital to pursue a career in neuropsychiatry. He set up a research group with main interests in the interface disorders between neurology and psychiatry, reflected in the developing recognition of neuropsychiatry and behavioural neurology as independent disciplines. The research group (Raymond-Way Unit) explored the behavioural consequences of neurological disorders and their treatment, with a major interest in epilepsy and movement disorders. His current writing and academic interests involve teaching and lecturing on neuroanatomical concepts relevant to understanding behaviour and its variations, in particular with an interest in neuroaesthetics and neurotheology, namely the cerebral basis of artistic and religious experiences.

Dr. George received his medical degree from the Medical University of South Carolina in Charleston in 1985, where he continued with dual residencies in neurology and psychiatry. He is board certified in both areas. He worked for one year (1990-91) as a Visiting Research Fellow in the Raymond Way Neuropsychiatry Research Group at the Institute of Neurology, London. He and Professor Trimble used pharmacology and imaging to study the overlaps between Obsessive-Compulsive Disorder and Gilles de la Tourette Syndrome. During this year he also worked on new functional imaging techniques (SPECT and PET) at the Institute of Nuclear Medicine, University College of London and Middlesex School of Medicine, London. He wrote one of the first textbooks in the new area of brain activation and imaging. Dr George then moved to Washington, DC, working with Dr. Robert Post in the Biological Psychiatry Branch of the Intramural National Institute of Mental Health. He was one of the first to use functional imaging (particularly oxygen PET) to assess brain changes associated with normal emotions, as well as using imaging to understand brain changes which occur in depression and mania. This imaging work directly led to his pioneering use of transcranial magnetic stimulation (TMS) as a probe of neuronal circuits regulating mood, and to clinical trials using TMS as an antidepressant. In 2008 prefrontal TMS was FDA approved as an antidepressant treatment. In 1995 he moved back to Charleston and built the functional neuroimaging division and brain stimulation laboratories. This imaging group has grown into the MUSC Center for Advanced Imaging Research, which is now part of the SC Brain Imaging Center of Excellence. He continues to use imaging and non-invasive stimulation, either separately or more recently in combination, to understand the brain regions involved in emotion regulation in health and disease. In 1998, he pioneered another new treatment for resistant depression, vagus nerve stimulation, that was recently FDA approved. He and his group have used MRI imaging to understand brain stimulation brain effects. He is on several editorial review boards, and has published over 200 scientific articles, and has written or edited 5 books. He is the editor-in-chief of a new journal, Brain Stimulation.
He has received several international awards, including the World Federation of Societies of Biological Psychiatry Lifetime Achievement Award (2007), the NARSAD Falcone Award (2008) and he was honored as one of 14 'Pioneers of Medical Progress' saluted in the August 2009 edition of US News & World Report.

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Editorials

Booknews

A comprehensive survey of concepts in biological psychology. Coverage includes principles of brain physiology, chemistry, and anatory; disorders of the limbic system; personality disorders; schizophrenia; epilepsies; and biological treatments. This second edition reflects the major advances in neuroanatomy, neurochemistry, genetics, and imaging techniques since the first edition in 1987. Of interest to advanced students, researchers, and clinicians psychiatry, psychology, and mental health care. Annotation c. Book News, Inc., Portland, OR (booknews.com)

From The Critics

Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is the second edition of this well-received textbook on the neurobiological aspects of psychiatry and is written by a well-known and influential researcher and clinician in the field.
Purpose: The purpose of this second edition is to document the advances in neuroanatomy, neurochemistry, genetics, and brain imaging that have occurred since Dr. Trimble wrote the first edition of his book. Dr. Trimble believes (as I do) that psychological theories of pathogenesis have been overtaken by a wealth of neurochemical and neuropathological hypotheses and findings. This book explains and teaches the reader these current theories in a very readable text.
Audience: The intended audience includes medical students, residents in psychiatry training programs, practicing psychiatrists, and psychologists interested in the current state of psychiatry. I would recommend this book to any individual involved in the care of the mentally ill. It is a shame that the recent neurobiological understanding of these illnesses has not filtered down or has been ignored by nonphysician mental health workers.
Features: The book features 12 chapters covering the important aspects of biological psychiatry (the title now is anachronistic). The book ends with a reference section and an index. The tables and figures are useful.
Assessment: The second edition of this book, which I looked forward to reading, was not disappointing. I highly recommend it.

From the Publisher

“This book therefore may be valuable to those engaged in clinical practice who wish to familiarize themselves with some of the basic concepts behind modern biological psychiatric research and the recent history of the field.” (Psychological Medicine, 2012)

"If you are going to choose where to fork out the money, it would be here, for the most practical understanding of brain-behavior science, and these authors I am sure will continue to be leaders in this field, with perhaps only Lishman challenging them for the buck." (Metapsychology, 25 June 2011)

"As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging descriptions not only of methodologies but also of the application of these in clinical settings." (AllVoices, 16 February 2011)

"An important contribution that should be read by psychopharmacologists, psychiatrists, neurologists and neuroscientists who wish to obtain an interesting and well-written account of the subject." (Human Psychopharmacology, 2010)

"Writing for medical students and for researchers and practitioners in fields that touch upon mental health, they begin by exploring principles of brain function and structure from perspectives of genetics, physiology, chemistry, and anatomy. Then they consider important brain-behavior relationships, and classifications and clinical investigations. Having set the stage, they proceed to describe biological aspects of personality disorders, anxiety disorders, the schizophrenias, affective disorders, the addictions and disorders of motivation, epilepsy, and the dementias." (SciTech Book News, December 2010)

3 Stars from Doody