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Geriatric Psychology, Cognitive Disorders, Memory Improvement, Cognitive Psychology
Can't Remember What I Forgot: Closing in on a Cure for Memory Loss by Sue Halpern — book cover

Can't Remember What I Forgot: Closing in on a Cure for Memory Loss

by Sue Halpern
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Overview

An essential behind-the-scenes foray into the world of cutting-edge memory research that unveils findings about memory loss only now available to general readers.

When Sue Halpern decided to emulate the first modern scientist of memory, Hermann Ebbinghaus, who experimented on himself, she had no idea that after a day of radioactive testing, her brain would become so “hot” that leaving through the front door of the lab would trigger the alarm. This was not the first time while researching Can’t Remember What I Forgot, part of which appeared in The New Yorker, that Halpern had her head examined, nor would it be the last.

Halpern spent years in the company of the neuroscientists, pharmacologists, psychologists, nutritionists, and inventors who are hunting for the genes and molecules, the drugs and foods, the machines, the prosthetics, the behaviors and therapies that will stave off Alzheimer’s and other forms of dementia and keep our minds–and memories–intact. Like many of us who have had a relative or friend succumb to memory loss, who are getting older, who are hearing statistics about our own chances of falling victim to dementia, who worry that each lapse of memory portends disease, Halpern wanted to find out what the experts really knew, what the bench scientists were working on, how close science is to a cure, to treatment, to accurate early diagnosis, and, of course, whether the crossword puzzles, sudokus, and ballroom dancing we’ve been told to take up can really keep us lucid or if they’re just something to do before the inevitable overtakes us.

Beautifully written, sharply observed, and deeply informed, Can’t Remember What I Forgot is a book full of vital information–and a solid dose of hope.

From the Hardcover edition.

Synopsis

An essential behind-the-scenes foray into the world of cutting-edge memory research that unveils findings about memory loss only now available to general readers. When Sue Halpern decided to emulate the first modern scientist of memory, Hermann Ebbinghaus, who experimented on himself, she had no idea that after a day of radioactive testing, her brain would become so “hot” that leaving through the front door of the lab would trigger the alarm. This was not the first time while researching Can’t Remember What I Forgot, part of which appeared in The New Yorker, that Halpern had her head examined, nor would it be the last. Halpern spent years in the company of the neuroscientists, pharmacologists, psychologists, nutritionists, and inventors who are hunting for the genes and molecules, the drugs and foods, the machines, the prosthetics, the behaviors and therapies that will stave off Alzheimer’s and other forms of dementia and keep our minds–and memories–intact. Like many of us who have had a relative or friend succumb to memory loss, who are getting older, who are hearing statistics about our own chances of falling victim to dementia, who worry that each lapse of memory portends disease, Halpern wanted to find out what the experts really knew, what the bench scientists were working on, how close science is to a cure, to treatment, to accurate early diagnosis, and, of course, whether the crossword puzzles, sudokus, and ballroom dancing we’ve been told to take up can really keep us lucid or if they’re just something to do before the inevitable overtakes us. Beautifully written, sharply observed, and deeply informed, Can’t Remember What I Forgot is a book full of vital information–and a solid dose of hope.

About the Author, Sue Halpern

SUE HALPERN received her doctorate from Oxford University in 1985 and first began teaching at Columbia University’s College of Physicians and Surgeons. She is the author of Four Wings and a Prayer, Migrations to Solitude, and two books of fiction. Her work has appeared in The New Yorker, the New York Times, Rolling Stone, Condé Nast Traveler, and The New York Review of Books, among other publications. She lives in Ripton, Vermont, with her husband, writer Bill McKibben, and their daughter, Sophie, and is a scholar-in-residence at Middlebury College.

From the Hardcover edition.

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Editorials

From Barnes & Noble

Everybody these days is worried about memory loss. With news that 10 million baby boomers will contract Alzheimer's, anxiety over possible dementia runs rampant, increasing with every lost set of keys, every forgotten phone number. Dissatisfied with vague news reports and anecdotal evidence, Dr. Sue Halpern decided to go directly to the experts. She queried neuroscientists, pharmacologists, psychologists, nutritionists, and inventors about what they're finding and what they expect to find about how we can best stay lucid. A solid dose of hope about an indispensable subject.

Publishers Weekly

Novelist and science writer Halpern (Four Wings and a Prayer) wades bravely into the morass of modern memory research to sort the truth from a wide assortment of "hyperbole and promises and platitudes." The news is mixed: most of us won't develop Alzheimer's, but everyone will suffer some memory loss. After describing the different types of memory, Halpern gamely undertakes a series of brain scans used to reveal brain damage and tries diagnostic tests that measure memory through the ability to recall words, images and smells. Researchers have identified a gene closely linked with Alzheimer's, but drugs to treat or prevent memory loss are still far from reality, Halpern says, adding that for many drug companies, the success of a remedy is measured only by how quickly it moves off the shelves. Armed with a mix of hope and healthy skepticism, the author also examines claims that eating chocolate (among other things) or solving puzzles can improve brain function. "So much of who we know ourselves to be comes from what we remember," Halpern writes, and her timely book offers a vivid, often amusing introduction to a science that touches us all. (May)

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Library Journal

Halpern's three-year inquiry into research on memory, aging, and Alzheimer's disease is an investigation of modern brain science rendered in creative nonfiction. Halpern gets to know a prominent neuroscientist, subjects herself to multiple tests (from paper-and-pencil tests to nuclear brain imaging), visits businesses involved in the quixotic race for memory-fixing drugs, and attends the Memory Olympics. She explains in plain English what science has discovered about learning and memory, what is currently agreed to improve memory, and what remains to be seen. No self-help book writer, Halpern has published four well-received books (e.g., Four Wings and a Prayer; Migrations to Solitude) and written for the New York Times, the New York Review of Books, and Slate magazine; she is frank and funny about her own fears and memory lapses and gently debunks memory-boosting fads, leaving the reader with few suggestions of what the ordinary person can do. Her book documents (with references) the great strides that have been made and holds out hope for real treatments for Alzheimer's and age-related memory loss. Educational, fabulously well written, and on a hot topic. Highly recommended for both public and academic libraries. [Halpern is married to nature writer Bill McKibben-Ed.]
—Nancy Fontaine

Kirkus Reviews

Engrossing review of the latest advances in the science of memory and brain disease. During the 1990s, Alzheimer's replaced AIDS as an American mass phobia, writes veteran science journalist Halpern (The Book of Hard Things, 2003, etc.). Polls place Alzheimer's second after cancer as the nation's most feared disease, and it's first among those older than 55. But, like thinning hair and wrinkles, memory problems occur during normal aging, she informs us. This is cold comfort to anyone who loses her keys or forgets to pay the phone bill, lapses that stimulated the middle-aged author to "get her head examined" and quiz the scientists doing the examining. Halpern intermixes her own experiences with interviews. Her subjects, most of them university faculty, do a good job explaining how we remember, what can go wrong and what they are doing about it. Heredity plays a role, but despite headlines regularly announcing the discovery of the Alzheimer's gene, it's unlikely that a single genetic trigger exists; instead, scientists have found plenty of genes that increase the risk. Detecting early memory loss has become a minor industry that often involves high-tech scans and MRIs, even though paper-and-pen tests work as well. (Halpern did both.) The author investigates research to boost memory and turns up one method that works: regular physical exercise. Folk wisdom to the contrary, doing crossword puzzles or math problems doesn't help. Many drugs increase memory in animals; given to humans, their success rate remains steady at zero. There is as yet no "cure," but Halpern stresses that breakthroughs occur much faster after scientists understand a disease, and Alzheimer's is no longer the bafflingpuzzle it once was. Researchers with new ideas and high-tech equipment are turning up specific anatomical, molecular and genetic abnormalities that govern memory and its loss. High-quality science writing: an illuminating picture of investigators at work and a lucid explication of their findings. Agent: Kim Witherspoon/InkWell Management

Book Details

Published
May 6, 2008
Publisher
Crown Publishing Group
Pages
288
ISBN
9780307409522

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