Overview
Here's today's most authoritative and up-to-date information on basic and clinical electrophysiology. The 4th Edition covers everything from fundamental explanations of currents and channels, through the theoretical and experimental bases of cardiac electrical activity and arrhythmias, to current clinical understandings of arrhythmias and their treatment—and features the most comprehensive updating and revision to date.
• Covers today's hottest topics, including HCN channels · stretch-activated channels · inward rectifier channels · contraction-excitation feedback · verve sprouting and arrhythmias · mechanisms of atrial fibrillation · mechanisms of ventricular fibrillation · transgenic and knockout models of cardiac arrhythmias · pharmacogenomics and cardiac arrhythmias · Brugada syndrome · and more.
• Features the expertise of 57 new contributors; and, existing contributors have revised and updated completely different chapters from previous editions.
• Presents 23 new chapters, including Stretch Activated Channels in the Heart · Biophysical Properties of Inward Rectifier Channels · Human Molecular Genetics and the Heart · Human Genetics of Channelopathies · and more.
• Includes revised and updated discussions of calcium channels · voltage regulated potassium channels · membrane pumps and exchangers · connexins · homomeric and heteromeric gap junctions · pharmacology of L-type and T-type channels in the heart · mechanisms of AV nodal excitability and propagation · theory of reentry · rotors and spiral waves in two dimensions · electrical remodeling and chronic atrial fibrillation · mechanisms of initiation of ventricular tachyarrhythmias · atrial fibrillation · ventricular tachycardia · long QT syndrome · Torsades de pointes · more!
The book contains predominantly black-and-white illustrations, with some color illustrations.
Editorials
From The Critics
Reviewer: Brian Olshansky, MD(Loyola University Stritch School of Medicine)Description: This second edition, edited by two internationally recognized experts and written by many contributors, purports to be a comprehensive, definitive text covering all of cardiac electrophysiology. A smaller first edition was published five years ago.
Purpose: The authors hope to provide a complete and authoritative book on cardiac electrophysiology. They include basic and clinical aspects of electrophysiology in this 14-section, 138-chapter book. The objectives are worthy and the book is needed. Generally, the authors meet their stated objectives.
Audience: The authors do not indicate the intended audience. A small audience of cardiac electrophysiology fellows and clinical and basic electrophysiologists (MDs and PhDs) will benefit. General cardiologists, surgeons, internists, and medical residents are not the target audience. The editors and 173 contributors are credible authorities, among the best known in their field.
Features: The contributors generously illustrate this book with black-and-white graphs, tables, figures, and charts. Most are of excellent quality, but some are too small. The color illustrations will benefit only a few. Most chapters contain pertinent references (in large numbers) but most references are over two to three years old. The table of contents is adequate. Some subjects are included in more than one section. Some chapters are narrow in scope with abstruse titles. The index is difficult to use. The book is large and heavy, but impressive and highly attractive.
Assessment: This book is one of the most comprehensive texts ever written in cardiac electrophysiology. The new information is enough to justify replacement of the previous edition. It is a monumental, multiauthored, book with numerous chapters. The content and presentation of most chapters are simply excellent, but the quality, format, and references vary. Although this will be a definitive text in cardiac electrophysiology, the editors underemphasize important (often, clinically based) subjects at the expense of more narrow topics. The large number of chapters (many of them short) makes the work disjointed and significant overlap exists. Some chapters are not complete and provide biased information. Despite these shortcomings, this edition is needed and welcomed. I highly recommended it for cardiac electrophysiologists, libraries, and bookstores.
Brian Olshansky
This second edition, edited by two internationally recognized experts and written by many contributors, purports to be a comprehensive, definitive text covering all of cardiac electrophysiology. A smaller first edition was published five years ago. The authors hope to provide a complete and authoritative book on cardiac electrophysiology. They include basic and clinical aspects of electrophysiology in this 14-section, 138-chapter book. The objectives are worthy and the book is needed. Generally, the authors meet their stated objectives. The authors do not indicate the intended audience. A small audience of cardiac electrophysiology fellows and clinical and basic electrophysiologists (MDs and PhDs) will benefit. General cardiologists, surgeons, internists, and medical residents are not the target audience. The editors and 173 contributors are credible authorities, among the best known in their field. The contributors generously illustrate this book with black-and-white graphs, tables, figures, and charts. Most are of excellent quality, but some are too small. The color illustrations will benefit only a few. Most chapters contain pertinent references (in large numbers) but most references are over two to three years old. The table of contents is adequate. Some subjects are included in more than one section. Some chapters are narrow in scope with abstruse titles. The index is difficult to use. The book is large and heavy, but impressive and highly attractive. This book is one of the most comprehensive texts ever written in cardiac electrophysiology. The new information is enough to justify replacement of the previous edition. It is a monumental, multiauthored, book with numerous chapters.The content and presentation of most chapters are simply excellent, but the quality, format, and references vary. Although this will be a definitive text in cardiac electrophysiology, the editors underemphasize important (often, clinically based) subjects at the expense of more narrow topics. The large number of chapters (many of them short) makes the work disjointed and significant overlap exists. Some chapters are not complete and provide biased information. Despite these shortcomings, this edition is needed and welcomed. I highly recommended it for cardiac electrophysiologists, libraries, and bookstores.3 Stars from Doody