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Overview
Now in its thirteenth edition and containing 115 new entries, Thomas H. Shepard's Catalog of Teratogenic Agents is the most comprehensive one-volume reference of its kind. Essential for geneticists, teratologists, and pharmacologists, it presents information on more than 3,200 teratogenic agents in a ready-reference format, covering pharmaceuticals, chemicals, environmental pollutants, food additives, household products, viruses, genes, and maternal conditions.
These agents are listed alphabetically, and each entry briefly summarizes research procedures and results. A complete list of references is included for each agent.
The Johns Hopkins University Press
The book contains no figures.
Synopsis
The most comprehensive one-volume guide of its kind, this standard reference work has been newly revised and expanded to present information on teratogenic agents in a ready-reference format. The tenth edition includes nearly 400 newly listed agents, approximately half of which are developmental genes that cause syndromes or congenital defects. It also reviews recent literature on clinical and experimental teratology, including important Japanese literature not easily available to researchers.
This latest edition of The Catalog of Teratogenic Agents emphasizes human data and covers pharmaceuticals, chemicals, environmental pollutants, food additives, household products, and viruses. A special effort has been made to obtain as much information as possible on drugs and other agents to which pregnant women may be exposed. Substances are listed alphabetically, and each entry briefly summarizes research procedures and results. As in previous editions, a complete list of references is included for each agent.
AUTHOR BIO:
Thomas H. Shepard, M.D., is a professor emeritis of pediatrics and former head of the Central Laboratory for Human Embryology at the University of Washington.
Journal of the American Pharmaceutical Association
A useful and exhaustive key to the literature.
Editorials
Teratology
A book that is familiar to many teratologists and should be familiar to all... The first edition of the catalog was a noble achievement and the subsequent editions have each embodied major improvements.Reproductive Toxicology
I continue to buy the latest bound edition of Shepard's Catalog on a regular basis. In fact, I make sure I have several copies available so I am never too far away from the Catalog.Reference Reviews
I can recommend it as a well-put together and easy to use reference.— John Goodier
Jeffrey C. Livingston
This is a very comprehensive reference that includes descriptions and evaluations of teratogenic agents, chemical compounds, and pharmaceuticals. Up-to-date information on drugs and other agents to which pregnant patients are exposed is provided. This book is a worthy shelf reference. This book is written for the practicing obstetrician who needs a reference to evaluate the numerous chemicals and drugs to which pregnant patients are exposed. The teratogenic effects of compounds from hail-dye to Agent Orange are explored. The index is cross-referenced and complete. The fifty-page author index is too excessive. This book can be used as a reference for the clinician or researcher. The strength is its completeness. With 2830 compounds, this book is more complete but not as thorough as Briggs' Drugs in Pregnancy and Lactation, 4th Edition (Lippincott William & Wilkins, 1994).Journal of the American Pharmaceutical Association
A useful and exhaustive key to the literature.Journal of Medical Genetics
Champions of the electronic age claim that reference books are now outdated, to be replaced by online databases and CD-ROMs . . .This new edition of a well-known and comprehensive catalog shows that there is still a place for high quality, well indexed, and up-to-date reference books . . . I would recommend this book for its breadth of entries and clarity of presentation. It shows that there is still a place for a good book in a world of electronic information.Anthony R. Scialli
It is good news that Johns Hopkins University Press continues to support frequent new editions of this classic reference. I have no reservations about coming up with the price of the book every three years or so. There is many a journal the subscription price of which far exceeds $30/year that does not get a fraction of the use of my Shepard.Teratology
A book that is familiar to many teratologists and should be familiar to all . . . The first edition of the catalog was a noble achievement and the subsequent editions have each embodied major improvements. [Shepard] deserves our support and help in continuing to update, improve, and expand hoped-for future editions.Journal of the American Pharmaceutical Association
A useful and exhaustive key to the literature.Journal of Medical Genetics
Champions of the electronic age claim that reference books are now outdated, to be replaced by online databases and CD-ROMs . . .This new edition of a well-known and comprehensive catalog shows that there is still a place for high quality, well indexed, and up-to-date reference books . . . I would recommend this book for its breadth of entries and clarity of presentation. It shows that there is still a place for a good book in a world of electronic information.Booknews
Included are proven, possible, and unlikely agents. Each entry includes synonyms, human data, a brief account of work published (species, dose, gestational age, type of defects produced), and references. Some 2,000 agents are cataloged, about 1200 of which can produce congenital anomalies in experimental animals; only about 30 are known to cause defects in the human. An important reference for obstetricians, pediatricians, geneticists, scientists who test pharmaceutical products, chemists developing new products. Annotation c. Book News, Inc., Portland, OR (booknews.com)From The Critics
Reviewer: Gilad A. Gross, MD(Washington University School of Medicine)Description: This catalog of teratogenic agents now in its 12th edition is devoted to describing the teratogenicity of many different agents/inciting events that span a multitude of categories. The latest edition continues the pattern of an update every three years and includes 300 additional entries, of which a third are newly listed agents.
Purpose: One of the main purposes of the catalog is to help link information on experimental teratogenic agents to congenital defects in humans. The gap between experimental teratology and human malformation is indeed quite wide. This book helps to bridge this gap by providing evidence for and against teratologic effect(s) of many agents and conditions. Seemingly every agent is considered, from chemicals to drugs, gene mutations and viruses. All species are considered, except those phylogenetically below the chick.
Audience: "This book is tailor-made for teratologists and geneticists and could be considered a "must have" for anyone providing genetic counseling to expectant parents. It would also be of benefit to anyone who is questioned about the safety of drugs and exposures during pregnancy. Hence, obstetricians/gynecologists and perinatal specialists would benefit from having this catalog. Researchers such as chemists could also find it useful. The authors have been publishing in teratology for many years. "
Features: This 3,000+ page catalog examines any and every possible teratologic agent and condition. The scope is so broad and the range so vast that literally no teratogen is missed. Cataloged agents include (but are not limited to): drugs, chemicals, viruses, bacteria, genetic alterations, deficiencies/excesses, extracts, medical conditions, procedures, occupational exposures, pesticides, and food dyes. This is the strength of this book. The vast amount of information is organized and easy to access. The agents are alphabetized and the index is listed dually for authors and for agents. Drugs are identified by their generic names and even the most complex chemical names are easily identified. Every entry is referenced at least once, and the majority have multiple references. There is nothing fancy about this catalog; it is not a flashy text, but it is not supposed to be.
Assessment: This is a wonderful complement to the many other resources available to clinicians and researchers involved in human reproduction (the books and web sites that complement this catalog are noted in the preface). It stands alone in its focus on the science of teratology. In the end, this is a comprehensive collection of agents that have been studied for teratogenicity in animals or humans.
5 Stars! from Doody