Toxicology, Pharmacology, Embryology, Biology - Developmental, Pediatrics

Methods in Developmental Toxicology and Biology

Name: Methods in Developmental Toxicology and Biology
Author: Renate Thiel
ISBN: 9780632041879

by Renate Thiel, Stephen Klug (Editor)

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Overview

Experimental work in animal systems involves investigations of organisms at the molecular and the cellular level. This book provides information on the latest research from the areas of both developmental toxicology and developmental biology. It covers a wide spectrum of the most powerful techniques currently available for studying the basic parameters of in vitro and in vivo development. The detailed theoretical background allows critical assessment and application of these techniques. The authors--all accomplished and world renowned experts in their topic areas--supply their accounts of the current research status in developmental toxicology and biology. This book is intended to catalyze exchange and collaboration between scientists in these disciplines and to provide newcomers with an entry to this research field.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorials

Leo Miller

This book provides a thorough explanation of model systems and techniques used in developmental toxicology and biology presented at the international symposium on Methods in Developmental Toxicology and Biology held in Berlin in 1995. The purpose is to provide an overview of the state-of-the-art techniques used in developmental toxicology. The editors state that their aim is to provide insight into the methodology available for studying various issues in developmental toxicology and biology. This book is aimed at specialist and nonspecialist researchers interested in developmental toxicology and biology. The editors and contributors are international experts in developmental toxicology. The different chapters have a nice balance of illustrations. When the international symposium on Methods in Developmental Toxicology and Biology took place in 1995, these techniques were up-to-date. However, due to the long publication time and the rapid advances in in vitro and in vivo test systems, they are not up-to-date any longer. For example, the references have not been updated beyond 1995. Nevertheless, this book does provide a complete description of many techniques currently in use and is recommended for purchase by libraries.

From The Critics

Reviewer:Leo Miller, PhD (University of Illinois at Chicago)
Description:This book provides a thorough explanation of model systems and techniques used in developmental toxicology and biology presented at the international symposium on Methods in Developmental Toxicology and Biology held in Berlin in 1995.
Purpose:The purpose is to provide an overview of the state-of-the-art techniques used in developmental toxicology. The editors state that their aim is to provide insight into the methodology available for studying various issues in developmental toxicology and biology.
Audience:This book is aimed at specialist and nonspecialist researchers interested in developmental toxicology and biology. The editors and contributors are international experts in developmental toxicology.
Features:The different chapters have a nice balance of illustrations.
Assessment:When the international symposium on Methods in Developmental Toxicology and Biology took place in 1995, these techniques were up-to-date. However, due to the long publication time and the rapid advances in in vitro and in vivo test systems, they are not up-to-date any longer. For example, the references have not been updated beyond 1995. Nevertheless, this book does provide a complete description of many techniques currently in use and is recommended for purchase by libraries.

Booknews

For scientists in both fields, describes a wide spectrum of techniques currently used to study the basic parameters of development "in vitro" and "in vivo", along with details of the theoretical background to facilitate their assessment and application. Reports on experimental work in animal systems at organism, molecular, and cellular levels. The topics include hematopoiesis in culture, the effect of dioxin on growth factor and receptor expression in the developing palate, the use of whole chick embryo cultures in physiology and development toxicology, gene targeting in embryonic stem cells, the experimental and molecular analysis of avian somite myogenesis, and a procedure to avoid inbreeding in a small closed population of marmosets. The 19 studies are from an international symposium held in Berlin, May to June 1995. Annotation c. by Book News, Inc., Portland, Or.