Biology - Microbiology, Immunology, Biology - Molecular Biology, Biology - Bacteriology, Cytology - General & Miscellaneous, Pathophysiology, Oncology - Basic Science

Cell Adhesion Molecules in Cancer and Inflammation

Name: Cell Adhesion Molecules in Cancer and Inflammation
Author: Agamemnon A. Epenetos
ISBN: 9783718655168

by Agamemnon A. Epenetos

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Overview

More than fifteen years have passed since the first definitive demonstration of functional activities mediating cell-matrix as well as cell-cell interactions. Since that time there has been increased interest in this subject since it is obvious that these interactions are key elements in the regulation of morphogenesis, tissue physiology and are disrupted in a variety of disease processes such as neoplasia and inflammation. A number of cell-cell and cell-matrix adhesion molecules have been identified and their structure, molecular genetics and biochemistry have been elucidated, and their normal function is beginning to be understood. However, the next challenge will be the clinical exploitation of adhesion molecules in the diagnosis and treatment of diseases.
Cell Adhesion Molecules in Cancer and Inflammation, the first volume in the Cell Adhesion and Communication book series, provides an up-to-date summary of the clinical applications of adhesion molecule research, focusing on the

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Begins a series for clinicians, graduate students, and researchers in academia, regulatory agencies, or industry, offering monographs both on classes of adhesion molecules and on the function of such molecules in particular systems. Here the emphasis is on the clinical evaluation of these molecules, particularly as novel biochemical and genetic markers to define tumor differentiation based on functional and morphological assessment, and also their potential use as targets for biological therapy. Includes ten pages of color plates. Annotation c. Book News, Inc., Portland, OR (booknews.com)