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Overview
This book presents a summary of the application and instrumentation of cell electrophoresis. The method of making cell purification and characterization possible according to the cellular negative surface charge density is discussed, and ideas for future developments are explained. The negative electrostatic forces at cell surfaces provide information about cell-cell interaction, blood vessel sealing, cytokine actions, cell transformation, ion transport phenomena, and other biological phenomena. Recalculations of the physical principles of cell electrophoresis reveal possibilities for removing disruptive factors caused by electrical current, heat, and sedimentation. The introduction of computer technology, the performance of simultaneous two-parameter measurements, and the application of cell-friendly but current-inert buffer systems render the method more reliable and efficient.
The book contains black-and-white illustrations.
Editorials
From The Critics
Reviewer: Alvin Telser, PhD(Northwestern University Feinberg School of Medicine)Description: This book presents an extensive theoretical and technically oriented discussion of a little-used technique in cell biology: cell electrophoresis. There is very little information on how the technique has been or might be used to help answer important questions about cells.
Purpose: This book was written to bring the state of knowledge in this field up to date. Because the technique of cell electrophoresis is not widely used, the main focus of the updating is of a theoretical and practical nature. As such, the objective of the author is achieved.
Audience: The author does not state for whom the book is written. Given the dry and technical nature of the writing, the main audience would seem to be specialists in the field. Because the technique is not widely used, the principle audience for this book would be very small. Although there are a few chapters presenting some data on cell electrophoresis of whole cells, they do not present any informative data, especially in light of other techniques based on flow cytometry that provide much more sensitive and comprehensive information about cell surfaces.
Features: The book is filled with mathematical formulas, graphs, tables and diagrams—almost too many. The few halftones are not very informative; there are a few photographs of pieces of equipment that are completely unlabeled. This is like looking at vacation photos of someone you don't know in a location you can't identify.
Assessment: This is a book of such a specialized nature so as to make it of limited use to a library. The theoretical and technical emphasis of this text belies the fact that there has been little useful scientific information that has been learned by using it. One might say that cell electrophoresis is an answer looking for a question.
Alvin Telser
This book presents an extensive theoretical and technically oriented discussion of a little-used technique in cell biology: cell electrophoresis. There is very little information on how the technique has been or might be used to help answer important questions about cells. This book was written to bring the state of knowledge in this field up to date. Because the technique of cell electrophoresis is not widely used, the main focus of the updating is of a theoretical and practical nature. As such, the objective of the author is achieved. The author does not state for whom the book is written. Given the dry and technical nature of the writing, the main audience would seem to be specialists in the field. Because the technique is not widely used, the principle audience for this book would be very small. Although there are a few chapters presenting some data on cell electrophoresis of whole cells, they do not present any informative data, especially in light of other techniques based on flow cytometry that provide much more sensitive and comprehensive information about cell surfaces. The book is filled with mathematical formulas, graphs, tables and diagrams--almost too many. The few halftones are not very informative; there are a few photographs of pieces of equipment that are completely unlabeled. This is like looking at vacation photos of someone you don't know in a location you can't identify. This is a book of such a specialized nature so as to make it of limited use to a library. The theoretical and technical emphasis of this text belies the fact that there has been little useful scientific information that has been learned by using it. One might say that cell electrophoresis is ananswer looking for a question.2 Stars from Doody