Contemporary Enzyme Kinetics and Mechanism

Gene A. Homandberg

This multiauthored second edition monograph is, as was the first edition published in 1983, a compilation of basic articles from the Enzymes and Kinetics series of Methods in Enzymology. The chapters were written by 19 contributors from various specialties. Most of the chapters have been updated, and 10 of the 17 chapters are new. "This monograph is meant to update the earlier volume to continue to provide assistance in design, execution and analysis of enzyme systems. Since the first edition in 1983, the dramatic growth of this area has necessitated a newer edition. For example, this edition has been updated extensively and, for example, now includes a very interesting chapter on site-directed mutagenesis. "Although the audience is meant to be biochemists and biophysicists, this monograph is an ideal primary textbook for students in this area. "This softcover book features the typical attractive Methods in Enzymology format, with a suitable number of black-and-white illustrations. The book also features a chapter on selected exercises and problems of both a quantitative and descriptive nature. "This book is highly recommended because it contains basic information and discussion that covers earlier work to more recent work on enzyme dynamics. It is also very important because of the increasing need for more nonspecialists to be able to study newly discovered or expressed enzymes.

From The Critics

Reviewer: Gene A. Homandberg, PhD (Rush Medical College of Rush University)
Description: This multiauthored second edition monograph is, as was the first edition published in 1983, a compilation of basic articles from the Enzymes and Kinetics series of Methods in Enzymology. The chapters were written by 19 contributors from various specialties. Most of the chapters have been updated, and 10 of the 17 chapters are new.
Purpose: This monograph is meant to update the earlier volume to continue to provide assistance in design, execution and analysis of enzyme systems. Since the first edition in 1983, the dramatic growth of this area has necessitated a newer edition. For example, this edition has been updated extensively and, for example, now includes a very interesting chapter on site-directed mutagenesis.
Audience: Although the audience is meant to be biochemists and biophysicists, this monograph is an ideal primary textbook for students in this area.
Features: This softcover book features the typical attractive Methods in Enzymology format, with a suitable number of black-and-white illustrations. The book also features a chapter on selected exercises and problems of both a quantitative and descriptive nature.
Assessment: This book is highly recommended because it contains basic information and discussion that covers earlier work to more recent work on enzyme dynamics. It is also very important because of the increasing need for more nonspecialists to be able to study newly discovered or expressed enzymes.

Booknews

A collection of articles from vols. 63, 64, 87, and 249 of Methods in Enzymology, describing widely used strategies in kinetic studies of enzyme action and offering exercises and problems. Subjects include cooperativity in enzyme function, product inhibition applications, mechanism-based enzyme inactivators, and hydrogen tunneling in enzyme catalysis. Includes the complete table of contents for each of the volumes used in the collection. This second edition contains articles from vol. 249, and ten of the 17 chapters are new. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody