Escherichia coli: Virulence Mechanisms of a Versatile Pathogen is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Escherichia coli: Virulence Mechanisms of a Versatile Pathogen concludes with a presentation of virulence factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.
Key Features
* Single source of information of E. coli pathogenesis
* Expert authors
* Comprehensive coverage
* Molecular mechanisms
* Biology, evolution and genomics
* Recent advances
Escherichia coli: Virulence Mechanisms of a Versatile Pathogen is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Escherichia coli: Virulence Mechanisms of a Versatile Pathogen concludes with a presentation of virulence factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research.
Key Features * Single source of information of E. coli pathogenesis * Expert authors * Comprehensive coverage * Molecular mechanisms * Biology, evolution and genomics * Recent advances
About the Author, Michael Donnenberg
Michael Donnenberg, MD is a Professor of Medicine and of Microbiology and Immunology at the University of Maryland. Dr. Donnenberg is a graduate of the Columbia University College of Physicians and Surgeons. He completed residency in Internal Medicine at what is now the Bayview Campus of Johns Hopkins and fellowship in Infectious Diseases at Tufts/New England Medical Center. After additional postdoctoral research training at the Center for Vaccine Development at the University of Maryland, Dr. Donnenberg joined the faculty in 1990.
Dr. Donnenberg’s research has focused on the molecular pathogenesis of infections due to Escherichia coli and on the biogenesis and function of bacterial surface appendages called Type IV Pili that are used by many pathogens to adhere to host cell surfaces. His work has been continuously funded by the National Institutes of Health for over twenty years and has resulted in the publication of over one hundred original manuscripts, reviews, and book chapters. He is a Fellow of the Infectious Diseases Society of America and the American Academy of Microbiology and a member of the American Society for Clinical Investigation. He is a recipient of the Oswald Avery Award from the Infectious Diseases Society of America.
Dr. Donnenberg is an active Infectious Diseases clinician and directs the Medical Scientist (MD/PhD) Program at the University of Maryland. He is also active in medical education and was an inaugural member of the Pass and Susel Academy of Academic Excellence at the University of Maryland.
"...an excellent and valuable reference work of general interest to microbiologists, infectious disease specialists, and food safety experts..."-ASM NEWS (June 2003)
