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Overview
In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.
Synopsis
Leading experts explain the many approaches to in vivo glucose sensing and point to new directions in research
Soon, people with diabetes will be able to depend on reliable, user-friendly in vivo glucose sensing systems to monitor their blood sugar levels. This volume brings readers fully up to date with recently commercialized in vivo sensing systems as well as current efforts to develop new and improved systems. The authors, leading pioneers and researchers in the field, include an MD and both academic and industrial researchers. Together, they review the many approaches to solving the "glucose sensing problem," helping readers apply the latest technology and advance their own research efforts.
Following an introductory chapter that sets forth the promise and challenges of glucose sensing, the book explores:
- Understanding and controlling the wound-healing response to facilitate implanted sensors
- State-of-the-technology implants, including electrochemical sensors and microdialysis devices
- New approaches to develop non-invasive, optical-based methods for measuring in vivo glucose
Chapters describe both analytical approaches and in vivo results, underscoring the need for a deep understanding of sensing technology as well as human anatomy and physiology. Throughout the book, detailed figures help readers better understand how and why various sensor systems work. In addition, color reproductions of tissue and histological slides draw attention to important features of the body tissue/sensor interface.
From established technologies to the most recent research advances, this book explains the current state of knowledge, sets forth the challenges, and points to new breakthroughs for in vivo glucose sensing.
Editorials
From the Publisher
"The book chapters are written by well-known experts in the field. The book can be considered as an important contribution to the literature on implantable and transdermal sensors and provides a description of the latest technology and a practically oriented approach to in vivo glucose sensing." (Anal Bioanal Chem, 2010)