Biochemistry - Lipids, Physiology, Pharmacology, Physiology - Biochemical Agents - General & Miscellaneous, Chemical Compounds & Molecules - General & Miscellaneous
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Overview
Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action.The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids.
Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.
Editorials
Booknews
Among the topics discussed in 12 contributions from international authorities: X-ray crystallographic studies; theoretical investigations; sex steroids and their analogs; stilbestrol estrogens; aromatase; vitamin D metabolites and their analogs; androgens and anabolics; neuromuscular blocking agents; and cariotonic steroids. Research in the area is fundamental to the rational design of steroid drugs. Annotation c. Book News, Inc., Portland, OR (booknews.com)Book Details
Published
August 14, 1992
Publisher
Boca Raton : CRC Press, c1992.
Pages
495
Format
Hardcover
ISBN
9780849369551