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Overview
Carbohydrates play a major role in the function and structure of the brain. In the past decade, tremendous progress has been made in understanding the structure, biosynthesis, and function of glycoconjugates found in the nervous system. The field of neuroglycobiology is now entering an exciting new phase with the use of molecular tools allowing us to manipulate the amount, as well as the temporal and spatially regulated expression, of those glycoconjugates. In recent years, we have gained important new knowledge on glycoproteins (polysialic acid, HNK-1 glycan), proteoglycans, and glycolipids.
'Neuroglycobiology' presents an integrative account of the latest developments in this field. This new volume in the Molecular and Cellular Neurobiology series starts by summarizing the historical background in identifying those glycoconjugates uniquely present in neural cells. It then goes on to summarize the current theories about their roles before considering future directions in research. This book presents an outstanding summary of the latest knowledge and perspectives in neural glycobiology.
Synopsis
Carbohydrates play a major role in the function and structure of the brain. In the past decade, tremendous progress has been made in understanding the structure, biosynthesis, and function of glycoconjugates found in the nervous system. The field of neuroglycobiology is now entering an exciting new phase with the use of molecular tools allowing us to manipulate the amount, as well as the temporal and spatially regulated expression, of those glycoconjugates. In recent years, we have gained important new knowledge on glycoproteins (polysialic acid, HNK-1 glycan), proteoglycans, and glycolipids.
'Neuroglycobiology' presents an integrative account of the latest developments in this field. This new volume in the Molecular and Cellular Neurobiology series starts by summarizing the historical background in identifying those glycoconjugates uniquely present in neural cells. It then goes on to summarize the current theories about their roles before considering future directions in research. This book presents an outstanding summary of the latest knowledge and perspectives in neural glycobiology.
Doody Review Services
Reviewer:Celso Agner, MD, MSc(University of Illinois at Chicago College of Medicine)
Description:Glycoproteins are important in the transmission of messages in the central nervous system. This book explores the topic further and attempts to give a better insight into this complex process.
Purpose:The purpose is to provide an in-depth treatment of neuroglycobiology, or the field in neuroscience related to the influence of glycolipids on the transmission of messages in the central nervous system. These worthy objectives are fully met by the authors.
Audience:Neuroscientists and neurobiologists are the main audience for this book.
Features:In the book's eight chapters, there is a progression of ideas from the basic description of glycolipids to their genetic role, biochemistry, and interference in the cell-messaging process. The chapters are well illustrated and clearly explain this complex topic in clear enough language even for the first-time reader. The pictures are of good quality.
Assessment:This is a moderately priced book useful to general neuroscience libraries. Although attempting a translational linking of information, it cannot be readily applied in the clinical arena.
Editorials
Reviewer: Celso Agner, MD, MS, MSc(Michigan Neurology Partners)
Description: Glycoproteins are important in the transmission of messages in the central nervous system. This book explores the topic further and attempts to give a better insight into this complex process.
Purpose: The purpose is to provide an in-depth treatment of neuroglycobiology, or the field in neuroscience related to the influence of glycolipids on the transmission of messages in the central nervous system. These worthy objectives are fully met by the authors.
Audience: Neuroscientists and neurobiologists are the main audience for this book.
Features: In the book's eight chapters, there is a progression of ideas from the basic description of glycolipids to their genetic role, biochemistry, and interference in the cell-messaging process. The chapters are well illustrated and clearly explain this complex topic in clear enough language even for the first-time reader. The pictures are of good quality.
Assessment: This is a moderately priced book useful to general neuroscience libraries. Although attempting a translational linking of information, it cannot be readily applied in the clinical arena.
3 Stars from Doody